Effects of local enemal matrix protein on osseointegration of different surface Titanium implants

The aim of this study is to investigate the osseointegration levels of implants with different surfaces locally applied with enamel matrix protein by biomechanical methods. Thirty adult female Spraque Dawley rats weighing 300–350 g were included in the study as subjects. The rats were divided into...

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Main Authors: Ozmen Istek, Kevser Sokmen, Erhan Cahit Ozcan, Murat Tanrisever, Turker Gelic, Umit Koray Can, Alihan Bozoglan, Serkan Dundar
Format: Article
Language:English
Published: Universidad del Zulia 2025-05-01
Series:Revista Científica
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Online Access:https://produccioncientificaluz.org/index.php/cientifica/article/view/43854
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author Ozmen Istek
Kevser Sokmen
Erhan Cahit Ozcan
Murat Tanrisever
Turker Gelic
Umit Koray Can
Alihan Bozoglan
Serkan Dundar
author_facet Ozmen Istek
Kevser Sokmen
Erhan Cahit Ozcan
Murat Tanrisever
Turker Gelic
Umit Koray Can
Alihan Bozoglan
Serkan Dundar
author_sort Ozmen Istek
collection DOAJ
description The aim of this study is to investigate the osseointegration levels of implants with different surfaces locally applied with enamel matrix protein by biomechanical methods. Thirty adult female Spraque Dawley rats weighing 300–350 g were included in the study as subjects. The rats were divided into 3 groups with 10 rats in each group: Machined Surface Group (n = 10), Sandblasted Large Acid Grid (SLA) Surface Group (n = 10) and Resorbable Blasting Material (RBM) Surface Group (n = 10). Titanium implants were surgically placed in the right tibias of the rats with sterile physiological serum cooling. Immediately before the implants were placed, local enamel matrix protein was applied to the prepared sockets and then the implants were placed. The rats were euthanized after waiting for osseointegration for four weeks and the implants were taken with the surrounding bone tissues after the soft tissues were removed. The bone–implant contact of all implants was analyzed by biomechanical method and recorded in Newton·cm-1 (N·cm-1). When the obtained biomechanical data were examined, the average bone–implant contact value was found to be 2.24 ± 0.67 (N·cm-1) in machined surface implants, 4.5 ± 1.36 (N·cm-1) in SLA surface implants and 3.24 ± 0.94 (N·cm-1) in RBM surface implants. A statistically difference was detected between machined surface implants and SLA surface implants (P<0.05; P=0.02). It can be stated that local enamel matrix protein application may increase bone–implant connection in SLA surface implants.
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spelling doaj-art-cae18fe5a6ef40df9c680fac95b78b3c2025-08-20T03:13:11ZengUniversidad del ZuliaRevista Científica0798-22592521-97152025-05-0135210.52973/rcfcv-e35625Effects of local enemal matrix protein on osseointegration of different surface Titanium implantsOzmen Istek0Kevser Sokmen1Erhan Cahit Ozcan2Murat Tanrisever3Turker Gelic4Umit Koray Can5Alihan Bozoglan6Serkan Dundar7Mus Alparslan University, Faculty of Health Sciences, Department of Nursing. Mus, Türkiye.Alanya Alaaddin Keykubat University, Faculty of Dentistry, Department of Periodontology. Antalya, Türkiye.Firat University, Faculty of Medicine, Department of Estetic, Plastic and Reconstructive Surgery. Elazig, Türkiye. Firat University, Faculty of Veterinary, Department of Surgery. Elazig, Türkiye.Firat University, Faculty of Veterinary, Department of Surgery. Elazig, Türkiye.Turkish Jockey Club. Elazig, Türkiye.Firat University, Faculty of Dentistry, Department of Periodontology. Elazig, Türkiye. Firat University, Faculty of Dentistry, Department of Periodontology. Elazig, Türkiye. The aim of this study is to investigate the osseointegration levels of implants with different surfaces locally applied with enamel matrix protein by biomechanical methods. Thirty adult female Spraque Dawley rats weighing 300–350 g were included in the study as subjects. The rats were divided into 3 groups with 10 rats in each group: Machined Surface Group (n = 10), Sandblasted Large Acid Grid (SLA) Surface Group (n = 10) and Resorbable Blasting Material (RBM) Surface Group (n = 10). Titanium implants were surgically placed in the right tibias of the rats with sterile physiological serum cooling. Immediately before the implants were placed, local enamel matrix protein was applied to the prepared sockets and then the implants were placed. The rats were euthanized after waiting for osseointegration for four weeks and the implants were taken with the surrounding bone tissues after the soft tissues were removed. The bone–implant contact of all implants was analyzed by biomechanical method and recorded in Newton·cm-1 (N·cm-1). When the obtained biomechanical data were examined, the average bone–implant contact value was found to be 2.24 ± 0.67 (N·cm-1) in machined surface implants, 4.5 ± 1.36 (N·cm-1) in SLA surface implants and 3.24 ± 0.94 (N·cm-1) in RBM surface implants. A statistically difference was detected between machined surface implants and SLA surface implants (P<0.05; P=0.02). It can be stated that local enamel matrix protein application may increase bone–implant connection in SLA surface implants. https://produccioncientificaluz.org/index.php/cientifica/article/view/43854Local enamel matrix proteintitanium implantosseointegrationbone implant connectionbone implant contact
spellingShingle Ozmen Istek
Kevser Sokmen
Erhan Cahit Ozcan
Murat Tanrisever
Turker Gelic
Umit Koray Can
Alihan Bozoglan
Serkan Dundar
Effects of local enemal matrix protein on osseointegration of different surface Titanium implants
Revista Científica
Local enamel matrix protein
titanium implant
osseointegration
bone implant connection
bone implant contact
title Effects of local enemal matrix protein on osseointegration of different surface Titanium implants
title_full Effects of local enemal matrix protein on osseointegration of different surface Titanium implants
title_fullStr Effects of local enemal matrix protein on osseointegration of different surface Titanium implants
title_full_unstemmed Effects of local enemal matrix protein on osseointegration of different surface Titanium implants
title_short Effects of local enemal matrix protein on osseointegration of different surface Titanium implants
title_sort effects of local enemal matrix protein on osseointegration of different surface titanium implants
topic Local enamel matrix protein
titanium implant
osseointegration
bone implant connection
bone implant contact
url https://produccioncientificaluz.org/index.php/cientifica/article/view/43854
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