Weighted Empirical Likelihood for Accelerated Life Model with Various Types of Censored Data

In analysis of survival data, the <i>Accelerated Life Model</i> (ALM) is one of the widely used semiparametric models, and we often encounter various types of censored survival data, such as right censored data, doubly censored data, interval censored data, partly interval-censored data,...

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Main Authors: Jian-Jian Ren, Yiming Lyu
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Stats
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Online Access:https://www.mdpi.com/2571-905X/7/3/57
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author Jian-Jian Ren
Yiming Lyu
author_facet Jian-Jian Ren
Yiming Lyu
author_sort Jian-Jian Ren
collection DOAJ
description In analysis of survival data, the <i>Accelerated Life Model</i> (ALM) is one of the widely used semiparametric models, and we often encounter various types of censored survival data, such as right censored data, doubly censored data, interval censored data, partly interval-censored data, etc. For complicated types of censored data, the studies of statistical inferences on the ALM are very technical and challenging mathematically, thus up to now little work has been done. In this article, we extend the concept of <i>weighted empirical likelihood</i> (WEL) from univariate case to multivariate case, and we apply it to the ALM, which leads to an estimation approach, called <i>weighted maximum likelihood estimator</i>, as well as the WEL based confidence interval for the regression parameter. Our proposed procedures are applicable to various types of censored data under a unified framework, and some simulation results are presented.
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spelling doaj-art-cacf793dde7c495699dc9bc7b232c1282025-08-20T01:55:52ZengMDPI AGStats2571-905X2024-09-017394495410.3390/stats7030057Weighted Empirical Likelihood for Accelerated Life Model with Various Types of Censored DataJian-Jian Ren0Yiming Lyu1Statistics Program, Department of Mathematics, University of Maryland, College Park, MD 20742, USAThe Janssen Pharmaceutical Company of Johnson & Johnson, New Brunswick, NJ 08933, USAIn analysis of survival data, the <i>Accelerated Life Model</i> (ALM) is one of the widely used semiparametric models, and we often encounter various types of censored survival data, such as right censored data, doubly censored data, interval censored data, partly interval-censored data, etc. For complicated types of censored data, the studies of statistical inferences on the ALM are very technical and challenging mathematically, thus up to now little work has been done. In this article, we extend the concept of <i>weighted empirical likelihood</i> (WEL) from univariate case to multivariate case, and we apply it to the ALM, which leads to an estimation approach, called <i>weighted maximum likelihood estimator</i>, as well as the WEL based confidence interval for the regression parameter. Our proposed procedures are applicable to various types of censored data under a unified framework, and some simulation results are presented.https://www.mdpi.com/2571-905X/7/3/57doubly censored dataempirical likelihoodinterval censored datamaximum likelihood estimatorpartly interval-censored dataright censored data
spellingShingle Jian-Jian Ren
Yiming Lyu
Weighted Empirical Likelihood for Accelerated Life Model with Various Types of Censored Data
Stats
doubly censored data
empirical likelihood
interval censored data
maximum likelihood estimator
partly interval-censored data
right censored data
title Weighted Empirical Likelihood for Accelerated Life Model with Various Types of Censored Data
title_full Weighted Empirical Likelihood for Accelerated Life Model with Various Types of Censored Data
title_fullStr Weighted Empirical Likelihood for Accelerated Life Model with Various Types of Censored Data
title_full_unstemmed Weighted Empirical Likelihood for Accelerated Life Model with Various Types of Censored Data
title_short Weighted Empirical Likelihood for Accelerated Life Model with Various Types of Censored Data
title_sort weighted empirical likelihood for accelerated life model with various types of censored data
topic doubly censored data
empirical likelihood
interval censored data
maximum likelihood estimator
partly interval-censored data
right censored data
url https://www.mdpi.com/2571-905X/7/3/57
work_keys_str_mv AT jianjianren weightedempiricallikelihoodforacceleratedlifemodelwithvarioustypesofcensoreddata
AT yiminglyu weightedempiricallikelihoodforacceleratedlifemodelwithvarioustypesofcensoreddata