Evaluation of automatic cell free DNA extraction metrics using different blood collection tubes

Evaluation of automatic cell free DNA extraction metrics using different blood collection tubes

Abstract Liquid biopsies and cell-free DNA (cfDNA) analysis are used in numerous clinical applications. The amount of cfDNA is generally limited and many approaches require assessment of individual molecules. Optimized pre-analytical steps are therefore fundamental for accurate interpretation. Here,...

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Bibliographic Details
Main Authors: Daniel Andersson, Helena Kristiansson, Manuel Luna Santamaría, Huma Zafar, Ivan Mijakovic, Åsa Torinsson Naluai, Anders Ståhlberg
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
Automated extraction
Cell-free DNA
Pre-analytics
Liquid biopsy
Blood plasma
Online Access:https://doi.org/10.1038/s41598-025-03508-4
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