Porphyromonas gingivalis hijacks mitophagy and lysosomal function to persist in endothelial cells

Porphyromonas gingivalis hijacks mitophagy and lysosomal function to persist in endothelial cells

IntroductionThe direct infection of endothelial cells by Porphyromonas gingivalis (P. gingivalis), a keystone periodontal pathogen, has been implicated in the development of atherosclerosis. While non-selective autophagy facilitates its intracellular persistence in endothelial cells, the role of sel...

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Bibliographic Details
Main Authors: Cheng Zheng, Jianmin Huang, Shengming Xu, Bin Lu, Hanxin Que, Tianhao Chen, Yubo Hou, Linlin He, Xia Fan, Fa-Ming Chen, Yi Wang, Hui Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Porphyromonas gingivalis
endothelial cells
mitophagy
lysosomal function
xenophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1613366/full
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