Vitamin D and Atopic Dermatitis in Childhood
Vitamin D features immunomodulatory effects on both the innate and adaptive immune systems, which may explain the growing evidence connecting vitamin D to allergic diseases. A wealth of studies describing a beneficial effect of vitamin D on atopic dermatitis (AD) prevalence and severity are known. H...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2015/257879 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849682822155993088 |
|---|---|
| author | Michelangelo Vestita Angela Filoni Maurizio Congedo Caterina Foti Domenico Bonamonte |
| author_facet | Michelangelo Vestita Angela Filoni Maurizio Congedo Caterina Foti Domenico Bonamonte |
| author_sort | Michelangelo Vestita |
| collection | DOAJ |
| description | Vitamin D features immunomodulatory effects on both the innate and adaptive immune systems, which may explain the growing evidence connecting vitamin D to allergic diseases. A wealth of studies describing a beneficial effect of vitamin D on atopic dermatitis (AD) prevalence and severity are known. However, observations linking high vitamin D levels to an increased risk of developing AD have also been published, effectively creating a controversy. In this paper, we review the existing literature on the association between AD and vitamin D levels, focusing on childhood. As of today, the role of vitamin D in AD is far from clear; additional studies are particularly needed in order to confirm the promising therapeutic role of vitamin D supplementation in childhood AD. |
| format | Article |
| id | doaj-art-cac6c2e6bf7d4deebeaf66fc468c6f9f |
| institution | DOAJ |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-cac6c2e6bf7d4deebeaf66fc468c6f9f2025-08-20T03:24:03ZengWileyJournal of Immunology Research2314-88612314-71562015-01-01201510.1155/2015/257879257879Vitamin D and Atopic Dermatitis in ChildhoodMichelangelo Vestita0Angela Filoni1Maurizio Congedo2Caterina Foti3Domenico Bonamonte4Section of Dermatology, Department of Biomedical Science and Human Oncology, University of Bari, 11 Piazza Giulio Cesare, 70124 Bari, ItalySection of Dermatology, Department of Biomedical Science and Human Oncology, University of Bari, 11 Piazza Giulio Cesare, 70124 Bari, ItalySection of Dermatology, Vito Fazzi Hospital, Piazza Filippo Muratore, 73100 Lecce, ItalySection of Dermatology, Department of Biomedical Science and Human Oncology, University of Bari, 11 Piazza Giulio Cesare, 70124 Bari, ItalySection of Dermatology, Department of Biomedical Science and Human Oncology, University of Bari, 11 Piazza Giulio Cesare, 70124 Bari, ItalyVitamin D features immunomodulatory effects on both the innate and adaptive immune systems, which may explain the growing evidence connecting vitamin D to allergic diseases. A wealth of studies describing a beneficial effect of vitamin D on atopic dermatitis (AD) prevalence and severity are known. However, observations linking high vitamin D levels to an increased risk of developing AD have also been published, effectively creating a controversy. In this paper, we review the existing literature on the association between AD and vitamin D levels, focusing on childhood. As of today, the role of vitamin D in AD is far from clear; additional studies are particularly needed in order to confirm the promising therapeutic role of vitamin D supplementation in childhood AD.http://dx.doi.org/10.1155/2015/257879 |
| spellingShingle | Michelangelo Vestita Angela Filoni Maurizio Congedo Caterina Foti Domenico Bonamonte Vitamin D and Atopic Dermatitis in Childhood Journal of Immunology Research |
| title | Vitamin D and Atopic Dermatitis in Childhood |
| title_full | Vitamin D and Atopic Dermatitis in Childhood |
| title_fullStr | Vitamin D and Atopic Dermatitis in Childhood |
| title_full_unstemmed | Vitamin D and Atopic Dermatitis in Childhood |
| title_short | Vitamin D and Atopic Dermatitis in Childhood |
| title_sort | vitamin d and atopic dermatitis in childhood |
| url | http://dx.doi.org/10.1155/2015/257879 |
| work_keys_str_mv | AT michelangelovestita vitamindandatopicdermatitisinchildhood AT angelafiloni vitamindandatopicdermatitisinchildhood AT mauriziocongedo vitamindandatopicdermatitisinchildhood AT caterinafoti vitamindandatopicdermatitisinchildhood AT domenicobonamonte vitamindandatopicdermatitisinchildhood |