Polypharmacy in Infectious Mononucleosis Management: Case Series

Background. Infectious mononucleosis is acute viral disease that often forces pediatricians, especially in outpatient departments, to prescribe antibiotics. However, viral infections even with prolonged fever and marked intoxication symptoms do not require antibacterial therapy. Unreasonable antibio...

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Main Authors: Artem A. Ivanov, Tatiana V. Kulichenko
Format: Article
Language:Russian
Published: Union of pediatricians of Russia 2023-01-01
Series:Педиатрическая фармакология
Subjects:
Online Access:https://www.pedpharma.ru/jour/article/view/2214
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author Artem A. Ivanov
Tatiana V. Kulichenko
author_facet Artem A. Ivanov
Tatiana V. Kulichenko
author_sort Artem A. Ivanov
collection DOAJ
description Background. Infectious mononucleosis is acute viral disease that often forces pediatricians, especially in outpatient departments, to prescribe antibiotics. However, viral infections even with prolonged fever and marked intoxication symptoms do not require antibacterial therapy. Unreasonable antibiotics’ administration leads to increase in antibiotic resistance, increase of treatment cost, and development of incorrect therapy understanding in patients. Clinical case description. The authors presented 3 clinical cases of infectious mononucleosis with typical course in children. All patients were unreasonably administered antibacterial therapy with three or more drugs in absence of any clinical and laboratory signs of bacterial infection. Conclusion. Patients with infectious mononucleosis do not require antibacterial therapy due to viral origin of the disease, regardless disease course duration and severity, except the cases with confirmed comorbid bacterial infection.
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series Педиатрическая фармакология
spelling doaj-art-cab2f7db071e420f995569f01adebc842025-08-20T03:19:39ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892023-01-0119541241610.15690/pf.v19i5.24621930Polypharmacy in Infectious Mononucleosis Management: Case SeriesArtem A. Ivanov0Tatiana V. Kulichenko1Morozov Children’s City HospitalPirogov Russian National Research Medical UniversityBackground. Infectious mononucleosis is acute viral disease that often forces pediatricians, especially in outpatient departments, to prescribe antibiotics. However, viral infections even with prolonged fever and marked intoxication symptoms do not require antibacterial therapy. Unreasonable antibiotics’ administration leads to increase in antibiotic resistance, increase of treatment cost, and development of incorrect therapy understanding in patients. Clinical case description. The authors presented 3 clinical cases of infectious mononucleosis with typical course in children. All patients were unreasonably administered antibacterial therapy with three or more drugs in absence of any clinical and laboratory signs of bacterial infection. Conclusion. Patients with infectious mononucleosis do not require antibacterial therapy due to viral origin of the disease, regardless disease course duration and severity, except the cases with confirmed comorbid bacterial infection.https://www.pedpharma.ru/jour/article/view/2214evidence-based medicinemanagementinfectious mononucleosisclinical caseantibioticspolypharmacyantibiotic resistance
spellingShingle Artem A. Ivanov
Tatiana V. Kulichenko
Polypharmacy in Infectious Mononucleosis Management: Case Series
Педиатрическая фармакология
evidence-based medicine
management
infectious mononucleosis
clinical case
antibiotics
polypharmacy
antibiotic resistance
title Polypharmacy in Infectious Mononucleosis Management: Case Series
title_full Polypharmacy in Infectious Mononucleosis Management: Case Series
title_fullStr Polypharmacy in Infectious Mononucleosis Management: Case Series
title_full_unstemmed Polypharmacy in Infectious Mononucleosis Management: Case Series
title_short Polypharmacy in Infectious Mononucleosis Management: Case Series
title_sort polypharmacy in infectious mononucleosis management case series
topic evidence-based medicine
management
infectious mononucleosis
clinical case
antibiotics
polypharmacy
antibiotic resistance
url https://www.pedpharma.ru/jour/article/view/2214
work_keys_str_mv AT artemaivanov polypharmacyininfectiousmononucleosismanagementcaseseries
AT tatianavkulichenko polypharmacyininfectiousmononucleosismanagementcaseseries