COMPARISON OF CLINICAL DIAGNOSIS AND HISTOPATHOLOGICAL FINDINGS IN CHRONIC PERIAPICAL LESIONS

Objective: To correlate the clinical and radiographic characteristics of various periapical diseases with their histopathological features identified in the post-surgical period. Methods: A morphological analysis of 80 biopsies obtained after periapical surgery was conducted, involving 52 (65%) w...

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Main Author: N.V. BAGRYANTSEVA
Format: Article
Language:English
Published: Avicenna Tajik State Medical University 2025-03-01
Series:Паёми Сино
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Online Access:https://doi.org/10.25005/2074-0581-2025-27-1-75-90
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author N.V. BAGRYANTSEVA
author_facet N.V. BAGRYANTSEVA
author_sort N.V. BAGRYANTSEVA
collection DOAJ
description Objective: To correlate the clinical and radiographic characteristics of various periapical diseases with their histopathological features identified in the post-surgical period. Methods: A morphological analysis of 80 biopsies obtained after periapical surgery was conducted, involving 52 (65%) women and 28 (35%) men aged 18 to 69. Radicular cysts, periapical granulomas, and abscesses are three lesions verified histologically. Before surgery, the lesion area was measured radiographically. Twelve months post-surgery, the effectiveness of the treatment was evaluated according to the von Arx and Kurt criteria. Informed consent was obtained from each patient for the processing of personal data. Descriptive statistical methods were utilized to analyze the collected data and investigate potential differences in frequency tables. Results: In the study, 62% of the lesions were identified as granulomas, 20% as cysts, and 18% as periapical abscesses. These findings indicate a low incidence of radicular cysts among periapical lesions, challenging the common belief that nearly half of all periapical lesions are cystic. Additionally, the results revealed that the lower first molar exhibited a high percentage of periapical lesions, primarily consistent with periapical granulomas, which were linked to inadequate treatment and underfilling of the root canals. Conclusion: This study established that most periapical lesions are granulomas and cysts. This finding underscores the prevalence of these lesion types as common outcomes of endodontic treatment directly linked to chronic processes occurring at the periapical site. However, it is important to note that the lesion size and radiographic appearance do not always correlate with the histopathological diagnosis, which can only be accurately determined through complete removal and thorough morphological examination of the lesion.
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spelling doaj-art-cab06cd7690e45ed84f940401b4f1d6a2025-08-20T03:09:42ZengAvicenna Tajik State Medical UniversityПаёми Сино2074-05812959-63272025-03-01271759010.25005/2074-0581-2025-27-1-75-90COMPARISON OF CLINICAL DIAGNOSIS AND HISTOPATHOLOGICAL FINDINGS IN CHRONIC PERIAPICAL LESIONSN.V. BAGRYANTSEVA0Department of Clinical Dentistry and Maxillofacial Surgery № 1, Yaroslavl State Medical University, Yaroslavl, Russian FederationObjective: To correlate the clinical and radiographic characteristics of various periapical diseases with their histopathological features identified in the post-surgical period. Methods: A morphological analysis of 80 biopsies obtained after periapical surgery was conducted, involving 52 (65%) women and 28 (35%) men aged 18 to 69. Radicular cysts, periapical granulomas, and abscesses are three lesions verified histologically. Before surgery, the lesion area was measured radiographically. Twelve months post-surgery, the effectiveness of the treatment was evaluated according to the von Arx and Kurt criteria. Informed consent was obtained from each patient for the processing of personal data. Descriptive statistical methods were utilized to analyze the collected data and investigate potential differences in frequency tables. Results: In the study, 62% of the lesions were identified as granulomas, 20% as cysts, and 18% as periapical abscesses. These findings indicate a low incidence of radicular cysts among periapical lesions, challenging the common belief that nearly half of all periapical lesions are cystic. Additionally, the results revealed that the lower first molar exhibited a high percentage of periapical lesions, primarily consistent with periapical granulomas, which were linked to inadequate treatment and underfilling of the root canals. Conclusion: This study established that most periapical lesions are granulomas and cysts. This finding underscores the prevalence of these lesion types as common outcomes of endodontic treatment directly linked to chronic processes occurring at the periapical site. However, it is important to note that the lesion size and radiographic appearance do not always correlate with the histopathological diagnosis, which can only be accurately determined through complete removal and thorough morphological examination of the lesion.https://doi.org/10.25005/2074-0581-2025-27-1-75-90periapical lesionscystgranulomaabscesshistopathologyradiography.
spellingShingle N.V. BAGRYANTSEVA
COMPARISON OF CLINICAL DIAGNOSIS AND HISTOPATHOLOGICAL FINDINGS IN CHRONIC PERIAPICAL LESIONS
Паёми Сино
periapical lesions
cyst
granuloma
abscess
histopathology
radiography.
title COMPARISON OF CLINICAL DIAGNOSIS AND HISTOPATHOLOGICAL FINDINGS IN CHRONIC PERIAPICAL LESIONS
title_full COMPARISON OF CLINICAL DIAGNOSIS AND HISTOPATHOLOGICAL FINDINGS IN CHRONIC PERIAPICAL LESIONS
title_fullStr COMPARISON OF CLINICAL DIAGNOSIS AND HISTOPATHOLOGICAL FINDINGS IN CHRONIC PERIAPICAL LESIONS
title_full_unstemmed COMPARISON OF CLINICAL DIAGNOSIS AND HISTOPATHOLOGICAL FINDINGS IN CHRONIC PERIAPICAL LESIONS
title_short COMPARISON OF CLINICAL DIAGNOSIS AND HISTOPATHOLOGICAL FINDINGS IN CHRONIC PERIAPICAL LESIONS
title_sort comparison of clinical diagnosis and histopathological findings in chronic periapical lesions
topic periapical lesions
cyst
granuloma
abscess
histopathology
radiography.
url https://doi.org/10.25005/2074-0581-2025-27-1-75-90
work_keys_str_mv AT nvbagryantseva comparisonofclinicaldiagnosisandhistopathologicalfindingsinchronicperiapicallesions