COMPARISON OF CLINICAL DIAGNOSIS AND HISTOPATHOLOGICAL FINDINGS IN CHRONIC PERIAPICAL LESIONS

Objective: To correlate the clinical and radiographic characteristics of various periapical diseases with their histopathological features identified in the post-surgical period. Methods: A morphological analysis of 80 biopsies obtained after periapical surgery was conducted, involving 52 (65%) w...

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Bibliographic Details
Main Author: N.V. BAGRYANTSEVA
Format: Article
Language:English
Published: Avicenna Tajik State Medical University 2025-03-01
Series:Паёми Сино
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Online Access:https://doi.org/10.25005/2074-0581-2025-27-1-75-90
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Summary:Objective: To correlate the clinical and radiographic characteristics of various periapical diseases with their histopathological features identified in the post-surgical period. Methods: A morphological analysis of 80 biopsies obtained after periapical surgery was conducted, involving 52 (65%) women and 28 (35%) men aged 18 to 69. Radicular cysts, periapical granulomas, and abscesses are three lesions verified histologically. Before surgery, the lesion area was measured radiographically. Twelve months post-surgery, the effectiveness of the treatment was evaluated according to the von Arx and Kurt criteria. Informed consent was obtained from each patient for the processing of personal data. Descriptive statistical methods were utilized to analyze the collected data and investigate potential differences in frequency tables. Results: In the study, 62% of the lesions were identified as granulomas, 20% as cysts, and 18% as periapical abscesses. These findings indicate a low incidence of radicular cysts among periapical lesions, challenging the common belief that nearly half of all periapical lesions are cystic. Additionally, the results revealed that the lower first molar exhibited a high percentage of periapical lesions, primarily consistent with periapical granulomas, which were linked to inadequate treatment and underfilling of the root canals. Conclusion: This study established that most periapical lesions are granulomas and cysts. This finding underscores the prevalence of these lesion types as common outcomes of endodontic treatment directly linked to chronic processes occurring at the periapical site. However, it is important to note that the lesion size and radiographic appearance do not always correlate with the histopathological diagnosis, which can only be accurately determined through complete removal and thorough morphological examination of the lesion.
ISSN:2074-0581
2959-6327