Virilisation during Pregnancy in a Patient with Metastatic Colorectal Cancer
This paper describes the case of a 25-year-old woman with virilisation occurring during pregnancy in the presence of metastatic colorectal cancer. Virilisation during pregnancy is rare. The potential causes include adrenal, foetal, or ovarian pathologies. The most common causes during pregnancy are...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2012/704039 |
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| _version_ | 1849473558059679744 |
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| author | F. Conway S. Jarvis M. Thornton |
| author_facet | F. Conway S. Jarvis M. Thornton |
| author_sort | F. Conway |
| collection | DOAJ |
| description | This paper describes the case of a 25-year-old woman with virilisation occurring during pregnancy in the presence of metastatic colorectal cancer. Virilisation during pregnancy is rare. The potential causes include adrenal, foetal, or ovarian pathologies. The most common causes during pregnancy are pregnancy luteoma and hyperreactio luteinalis. The incidence of cancer during pregnancy is rare and the incidence of colorectal cancer (CRC) in pregnancy is even rarer. The presenting signs and symptoms of CRC can be confused with symptoms commonly encountered during pregnancy, thereby delaying diagnosis and commencement of treatment. Diagnosis and staging also proves more problematic in the pregnant patient as the usual modalities of colonoscopy with biopsy and imaging with CT are relatively contraindicated. Treatment is dependent on gestational age of the foetus. There is currently no agreed best practice as to the role of prophylactic oophorectomy in the prevention of metachronous ovarian metastases. Surgical and adjuvant treatments have implications for females of child-bearing age. |
| format | Article |
| id | doaj-art-caad2225c2724e6eb4350c4bca5ec637 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-caad2225c2724e6eb4350c4bca5ec6372025-08-20T03:24:06ZengWileyCase Reports in Surgery2090-69002090-69192012-01-01201210.1155/2012/704039704039Virilisation during Pregnancy in a Patient with Metastatic Colorectal CancerF. Conway0S. Jarvis1M. Thornton2General Surgical Department, Wishaw General Hospital, 50 Netherton Street, Wishaw ML2 0DP, UKClinical Laboratories, Wishaw General Hospital, 50 Netherton Street, Wishaw ML2 0DP, UKGeneral Surgical Department, Wishaw General Hospital, 50 Netherton Street, Wishaw ML2 0DP, UKThis paper describes the case of a 25-year-old woman with virilisation occurring during pregnancy in the presence of metastatic colorectal cancer. Virilisation during pregnancy is rare. The potential causes include adrenal, foetal, or ovarian pathologies. The most common causes during pregnancy are pregnancy luteoma and hyperreactio luteinalis. The incidence of cancer during pregnancy is rare and the incidence of colorectal cancer (CRC) in pregnancy is even rarer. The presenting signs and symptoms of CRC can be confused with symptoms commonly encountered during pregnancy, thereby delaying diagnosis and commencement of treatment. Diagnosis and staging also proves more problematic in the pregnant patient as the usual modalities of colonoscopy with biopsy and imaging with CT are relatively contraindicated. Treatment is dependent on gestational age of the foetus. There is currently no agreed best practice as to the role of prophylactic oophorectomy in the prevention of metachronous ovarian metastases. Surgical and adjuvant treatments have implications for females of child-bearing age.http://dx.doi.org/10.1155/2012/704039 |
| spellingShingle | F. Conway S. Jarvis M. Thornton Virilisation during Pregnancy in a Patient with Metastatic Colorectal Cancer Case Reports in Surgery |
| title | Virilisation during Pregnancy in a Patient with Metastatic Colorectal Cancer |
| title_full | Virilisation during Pregnancy in a Patient with Metastatic Colorectal Cancer |
| title_fullStr | Virilisation during Pregnancy in a Patient with Metastatic Colorectal Cancer |
| title_full_unstemmed | Virilisation during Pregnancy in a Patient with Metastatic Colorectal Cancer |
| title_short | Virilisation during Pregnancy in a Patient with Metastatic Colorectal Cancer |
| title_sort | virilisation during pregnancy in a patient with metastatic colorectal cancer |
| url | http://dx.doi.org/10.1155/2012/704039 |
| work_keys_str_mv | AT fconway virilisationduringpregnancyinapatientwithmetastaticcolorectalcancer AT sjarvis virilisationduringpregnancyinapatientwithmetastaticcolorectalcancer AT mthornton virilisationduringpregnancyinapatientwithmetastaticcolorectalcancer |