Neurogenic Pulmonary Edema Associated with Underlying Lung Disease after a Breakthrough Seizure

Neurogenic pulmonary edema (NPE) can result from various central nervous system disorders such as brain malignancies, traumatic brain injuries, infections, and seizures. Although the pathogenesis is not completely understood, NPE creates an increase in pulmonary interstitial and alveolar fluid. It h...

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Main Authors: Gaurav Dutta, Spiro Demetis
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/560942
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author Gaurav Dutta
Spiro Demetis
author_facet Gaurav Dutta
Spiro Demetis
author_sort Gaurav Dutta
collection DOAJ
description Neurogenic pulmonary edema (NPE) can result from various central nervous system disorders such as brain malignancies, traumatic brain injuries, infections, and seizures. Although the pathogenesis is not completely understood, NPE creates an increase in pulmonary interstitial and alveolar fluid. It has been reported with prolonged seizure activity. Treatment for NPE is largely supportive. If unrecognized, it can lead to hypoxia and respiratory arrest. We report a case of NPE in a middle-aged female patient following a breakthrough seizure in whom an immunological cause for respiratory findings was high on the differential list, based on her past medical history and chronicity of symptoms. Rapid symptomatic and radiological improvement following hospitalization led to the correct diagnosis.
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spelling doaj-art-caab0c2a5835408697d094f50aedb45a2025-08-20T03:24:06ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/560942560942Neurogenic Pulmonary Edema Associated with Underlying Lung Disease after a Breakthrough SeizureGaurav Dutta0Spiro Demetis1Department of Internal Medicine, Lutheran Medical Center, 150 55th Street, Brooklyn, NY 11209, USADepartment of Internal Medicine, Lutheran Medical Center, 150 55th Street, Brooklyn, NY 11209, USANeurogenic pulmonary edema (NPE) can result from various central nervous system disorders such as brain malignancies, traumatic brain injuries, infections, and seizures. Although the pathogenesis is not completely understood, NPE creates an increase in pulmonary interstitial and alveolar fluid. It has been reported with prolonged seizure activity. Treatment for NPE is largely supportive. If unrecognized, it can lead to hypoxia and respiratory arrest. We report a case of NPE in a middle-aged female patient following a breakthrough seizure in whom an immunological cause for respiratory findings was high on the differential list, based on her past medical history and chronicity of symptoms. Rapid symptomatic and radiological improvement following hospitalization led to the correct diagnosis.http://dx.doi.org/10.1155/2012/560942
spellingShingle Gaurav Dutta
Spiro Demetis
Neurogenic Pulmonary Edema Associated with Underlying Lung Disease after a Breakthrough Seizure
Case Reports in Medicine
title Neurogenic Pulmonary Edema Associated with Underlying Lung Disease after a Breakthrough Seizure
title_full Neurogenic Pulmonary Edema Associated with Underlying Lung Disease after a Breakthrough Seizure
title_fullStr Neurogenic Pulmonary Edema Associated with Underlying Lung Disease after a Breakthrough Seizure
title_full_unstemmed Neurogenic Pulmonary Edema Associated with Underlying Lung Disease after a Breakthrough Seizure
title_short Neurogenic Pulmonary Edema Associated with Underlying Lung Disease after a Breakthrough Seizure
title_sort neurogenic pulmonary edema associated with underlying lung disease after a breakthrough seizure
url http://dx.doi.org/10.1155/2012/560942
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