Pyoderma gangrenosum: update and guidance

Introduction: The pyoderma gangrenosum (PG) is a neutrophilic disease, rare but with a poor outcome. The Capitulum of Wound treatment of the Brazilian Society of Plastic Surgery (SBCP) promoted a discussion with the Brazilian societies of Dermatology and Rheumatology to extract the best pro...

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Main Authors: Luiz Felipe Duarte Fernandes Vieira, Carlos Lacerda Andrade Almeida, Alexandre Wagner de Souza, Jozelia Rêgo, Everton Siviero do Vale, Jose Roberto Pereira Pegas
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2022-12-01
Series:Revista Brasileira de Cirurgia Plástica
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Online Access:http://www.rbcp.org.br/export-pdf/3204/en_v37n4a06.pdf
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author Luiz Felipe Duarte Fernandes Vieira
Carlos Lacerda Andrade Almeida
Alexandre Wagner de Souza
Jozelia Rêgo
Everton Siviero do Vale
Jose Roberto Pereira Pegas
author_facet Luiz Felipe Duarte Fernandes Vieira
Carlos Lacerda Andrade Almeida
Alexandre Wagner de Souza
Jozelia Rêgo
Everton Siviero do Vale
Jose Roberto Pereira Pegas
author_sort Luiz Felipe Duarte Fernandes Vieira
collection DOAJ
description Introduction: The pyoderma gangrenosum (PG) is a neutrophilic disease, rare but with a poor outcome. The Capitulum of Wound treatment of the Brazilian Society of Plastic Surgery (SBCP) promoted a discussion with the Brazilian societies of Dermatology and Rheumatology to extract the best procedures in diagnostic and treatment. Methods: Broad review of published articles related to the subject and compilation of guidelines of diagnostic and treatment by two advisors of each involved society, plastic surgery, dermatology and rheumatology. Results: The PG is not an exclusion disease anymore, with well defined criteria for its diagnostic and literature based treatment, refined by the authors, including the use of biological therapies. Conclusion: The PG remains challenging, but systematizing the investigation and the use of new drugs has opened a new horizon of treatments, interfering in the pathophysiology in a positive manner with fewer side effects than immunosuppressive therapy alone.
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language English
publishDate 2022-12-01
publisher Thieme Revinter Publicações Ltda.
record_format Article
series Revista Brasileira de Cirurgia Plástica
spelling doaj-art-caa8ecd4a18e4df79bfadf165c62e8aa2025-08-20T03:38:49ZengThieme Revinter Publicações Ltda.Revista Brasileira de Cirurgia Plástica1983-51752177-12352022-12-01370442343010.5935/2177-1235.2022RBCP.671-enPyoderma gangrenosum: update and guidanceLuiz Felipe Duarte Fernandes Vieira0Carlos Lacerda Andrade Almeida1Alexandre Wagner de Souza2Jozelia Rêgo3Everton Siviero do Vale4Jose Roberto Pereira Pegas5Hospital Agamenon Magalhaes, Departamento de Cirurgia Plástica, Recife, PE, BrazilHospital Agamenon Magalhaes, Departamento de Cirurgia Plástica, Recife, PE, BrazilUniversidade Federal de São Paulo UNIFESP-EPM, Disciplina de Reumatologia, São Paulo, SP, BrazilUniversidade Federal de Goiás Faculdade de Medicina Serviço de Reumatologia, Goiânia, GO, BrazilUniversidade Federal de Minas Gerais, Departamento de Dermatologia, Belo Horizonte, MG, BrazilFaculdade de Medicina de Jundiaí, Departamento de Dermatologia, Jundiaí, SP, BrazilIntroduction: The pyoderma gangrenosum (PG) is a neutrophilic disease, rare but with a poor outcome. The Capitulum of Wound treatment of the Brazilian Society of Plastic Surgery (SBCP) promoted a discussion with the Brazilian societies of Dermatology and Rheumatology to extract the best procedures in diagnostic and treatment. Methods: Broad review of published articles related to the subject and compilation of guidelines of diagnostic and treatment by two advisors of each involved society, plastic surgery, dermatology and rheumatology. Results: The PG is not an exclusion disease anymore, with well defined criteria for its diagnostic and literature based treatment, refined by the authors, including the use of biological therapies. Conclusion: The PG remains challenging, but systematizing the investigation and the use of new drugs has opened a new horizon of treatments, interfering in the pathophysiology in a positive manner with fewer side effects than immunosuppressive therapy alone.http://www.rbcp.org.br/export-pdf/3204/en_v37n4a06.pdfpyoderma gangrenosumpyodermaskin diseasesautoimmunityneutrophilssocietiesmedical.
spellingShingle Luiz Felipe Duarte Fernandes Vieira
Carlos Lacerda Andrade Almeida
Alexandre Wagner de Souza
Jozelia Rêgo
Everton Siviero do Vale
Jose Roberto Pereira Pegas
Pyoderma gangrenosum: update and guidance
Revista Brasileira de Cirurgia Plástica
pyoderma gangrenosum
pyoderma
skin diseases
autoimmunity
neutrophils
societies
medical.
title Pyoderma gangrenosum: update and guidance
title_full Pyoderma gangrenosum: update and guidance
title_fullStr Pyoderma gangrenosum: update and guidance
title_full_unstemmed Pyoderma gangrenosum: update and guidance
title_short Pyoderma gangrenosum: update and guidance
title_sort pyoderma gangrenosum update and guidance
topic pyoderma gangrenosum
pyoderma
skin diseases
autoimmunity
neutrophils
societies
medical.
url http://www.rbcp.org.br/export-pdf/3204/en_v37n4a06.pdf
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AT alexandrewagnerdesouza pyodermagangrenosumupdateandguidance
AT jozeliarego pyodermagangrenosumupdateandguidance
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