Circulating mitochondrial DNA signature in cardiometabolic patients

Circulating mitochondrial DNA signature in cardiometabolic patients

Abstract Background Mitochondrial dysfunction is a hallmark of cardiometabolic diseases. Circulating mitochondrial DNA (mtDNA) profiles could refine risk stratification, but current methods do not account for different fractions of circulating mtDNA. We investigated whether patients with type 2 diab...

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Bibliographic Details
Main Authors: Alessandro Mengozzi, Silvia Armenia, Nicolò De Biase, Lavinia Del Punta, Federica Cappelli, Emiliano Duranti, Virginia Nannipieri, Rossana Remollino, Domenico Tricò, Agostino Virdis, Stefano Taddei, Nicola Riccardo Pugliese, Stefano Masi
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Cardiovascular Diabetology
Subjects:
Circulating mitochondrial DNA
Heart failure
Type 2 diabetes
Effort intolerance
Congestion
Online Access:https://doi.org/10.1186/s12933-025-02656-1
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