Guillain-Barré Syndrome Associated with Primary Parvovirus B19 Infection in an HIV-1-Infected Patient
Parvovirus B19 (B19V) infection has rarely been reported as responsible for Guillain-Barré syndrome (GBS). We present the case of a 63-year-old man with AIDS who presented with rapidly progressing weakness of his inferior limbs and a newly appeared pancytopenia. CSF examination and electromyography...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/140780 |
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| author | Caroline Bucher Praz Cédric Dessimoz Frank Bally Sitthided Reymond Nicolas Troillet |
| author_facet | Caroline Bucher Praz Cédric Dessimoz Frank Bally Sitthided Reymond Nicolas Troillet |
| author_sort | Caroline Bucher Praz |
| collection | DOAJ |
| description | Parvovirus B19 (B19V) infection has rarely been reported as responsible for Guillain-Barré syndrome (GBS). We present the case of a 63-year-old man with AIDS who presented with rapidly progressing weakness of his inferior limbs and a newly appeared pancytopenia. CSF examination and electromyography were characteristic for GBS. Very high CSF and serum B19V DNA concentrations were present, in the absence of IgG or IgM against B19V. The neurologic and hematologic abnormalities improved after a 5-day course of i.v. immunoglobulins in parallel with a dramatic decrease in the B19V viral load. |
| format | Article |
| id | doaj-art-ca95ce60f2c14456b76ea83734b10d80 |
| institution | OA Journals |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-ca95ce60f2c14456b76ea83734b10d802025-08-20T02:19:34ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/140780140780Guillain-Barré Syndrome Associated with Primary Parvovirus B19 Infection in an HIV-1-Infected PatientCaroline Bucher Praz0Cédric Dessimoz1Frank Bally2Sitthided Reymond3Nicolas Troillet4Service of Internal Medicine, Department of Internal Medicine, Mid-Valais Hospital Center, 81, Avenue Grand-Champsec, 1950 Sion, SwitzerlandService of Infectious Diseases, Central Institute of the Valais Hospitals, 86, Avenue Grand-Champsec, 1950 Sion, SwitzerlandService of Infectious Diseases, Central Institute of the Valais Hospitals, 86, Avenue Grand-Champsec, 1950 Sion, SwitzerlandService of Neurology, Department of Internal Medicine, Mid-Valais Hospital Center, 81, Avenue Grand-Champsec, 1950 Sion, SwitzerlandService of Infectious Diseases, Central Institute of the Valais Hospitals, 86, Avenue Grand-Champsec, 1950 Sion, SwitzerlandParvovirus B19 (B19V) infection has rarely been reported as responsible for Guillain-Barré syndrome (GBS). We present the case of a 63-year-old man with AIDS who presented with rapidly progressing weakness of his inferior limbs and a newly appeared pancytopenia. CSF examination and electromyography were characteristic for GBS. Very high CSF and serum B19V DNA concentrations were present, in the absence of IgG or IgM against B19V. The neurologic and hematologic abnormalities improved after a 5-day course of i.v. immunoglobulins in parallel with a dramatic decrease in the B19V viral load.http://dx.doi.org/10.1155/2012/140780 |
| spellingShingle | Caroline Bucher Praz Cédric Dessimoz Frank Bally Sitthided Reymond Nicolas Troillet Guillain-Barré Syndrome Associated with Primary Parvovirus B19 Infection in an HIV-1-Infected Patient Case Reports in Medicine |
| title | Guillain-Barré Syndrome Associated with Primary Parvovirus B19 Infection in an HIV-1-Infected Patient |
| title_full | Guillain-Barré Syndrome Associated with Primary Parvovirus B19 Infection in an HIV-1-Infected Patient |
| title_fullStr | Guillain-Barré Syndrome Associated with Primary Parvovirus B19 Infection in an HIV-1-Infected Patient |
| title_full_unstemmed | Guillain-Barré Syndrome Associated with Primary Parvovirus B19 Infection in an HIV-1-Infected Patient |
| title_short | Guillain-Barré Syndrome Associated with Primary Parvovirus B19 Infection in an HIV-1-Infected Patient |
| title_sort | guillain barre syndrome associated with primary parvovirus b19 infection in an hiv 1 infected patient |
| url | http://dx.doi.org/10.1155/2012/140780 |
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