Ten-year experience in management of diabetic ketoacidosis and ketosis: 140 episodes at pediatric age

One hundred and forty episodes in 112 patients (58 boys) with diabetic ketoacidosis (96 episodes) and diabetic ketosis (44 episodes) were studied to elucidate the clinical and laboratory risk factors for altered level of consciousness at presentation and to analyze the outcome of a distinct p...

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Main Authors: Nuren Yordam, E Nazli Gönç, Nurgün Kandemir, Ayfer Alikaşifoğlu, Alev Ozön
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2005-10-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/2741
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author Nuren Yordam
E Nazli Gönç
Nurgün Kandemir
Ayfer Alikaşifoğlu
Alev Ozön
author_facet Nuren Yordam
E Nazli Gönç
Nurgün Kandemir
Ayfer Alikaşifoğlu
Alev Ozön
author_sort Nuren Yordam
collection DOAJ
description One hundred and forty episodes in 112 patients (58 boys) with diabetic ketoacidosis (96 episodes) and diabetic ketosis (44 episodes) were studied to elucidate the clinical and laboratory risk factors for altered level of consciousness at presentation and to analyze the outcome of a distinct protocol in the treatment of diabetic ketoacidosis. The patients were analyzed according to demographic data and clinical and laboratory findings at admission. The treatment protocol involved use of 0.45% sodium chloride (NaCl) in 2.5% dextrose as the initial fluid therapy following volume expansion. Dextrose content of the fluid was doubled once the serum glucose level fell below 250 mg/dl. The mean ages at presentation with diabetic ketoacidosis and ketosis were 10.3 +/- 4.4 and 10.2 +/- 4.0 years, respectively. Thirty-one percent of patients had altered consciousness at presentation. The level of consciousness correlated negatively with serum bicarbonate level (r=-0.485; p
format Article
id doaj-art-ca8e3cfadfbf48e18c448b5b0d17344f
institution DOAJ
issn 0041-4301
2791-6421
language English
publishDate 2005-10-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-ca8e3cfadfbf48e18c448b5b0d17344f2025-08-20T02:55:39ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212005-10-01474Ten-year experience in management of diabetic ketoacidosis and ketosis: 140 episodes at pediatric ageNuren Yordam0E Nazli GönçNurgün KandemirAyfer AlikaşifoğluAlev OzönEndocrinology Unit, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey. One hundred and forty episodes in 112 patients (58 boys) with diabetic ketoacidosis (96 episodes) and diabetic ketosis (44 episodes) were studied to elucidate the clinical and laboratory risk factors for altered level of consciousness at presentation and to analyze the outcome of a distinct protocol in the treatment of diabetic ketoacidosis. The patients were analyzed according to demographic data and clinical and laboratory findings at admission. The treatment protocol involved use of 0.45% sodium chloride (NaCl) in 2.5% dextrose as the initial fluid therapy following volume expansion. Dextrose content of the fluid was doubled once the serum glucose level fell below 250 mg/dl. The mean ages at presentation with diabetic ketoacidosis and ketosis were 10.3 +/- 4.4 and 10.2 +/- 4.0 years, respectively. Thirty-one percent of patients had altered consciousness at presentation. The level of consciousness correlated negatively with serum bicarbonate level (r=-0.485; phttps://turkjpediatr.org/article/view/2741
spellingShingle Nuren Yordam
E Nazli Gönç
Nurgün Kandemir
Ayfer Alikaşifoğlu
Alev Ozön
Ten-year experience in management of diabetic ketoacidosis and ketosis: 140 episodes at pediatric age
The Turkish Journal of Pediatrics
title Ten-year experience in management of diabetic ketoacidosis and ketosis: 140 episodes at pediatric age
title_full Ten-year experience in management of diabetic ketoacidosis and ketosis: 140 episodes at pediatric age
title_fullStr Ten-year experience in management of diabetic ketoacidosis and ketosis: 140 episodes at pediatric age
title_full_unstemmed Ten-year experience in management of diabetic ketoacidosis and ketosis: 140 episodes at pediatric age
title_short Ten-year experience in management of diabetic ketoacidosis and ketosis: 140 episodes at pediatric age
title_sort ten year experience in management of diabetic ketoacidosis and ketosis 140 episodes at pediatric age
url https://turkjpediatr.org/article/view/2741
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AT nurgunkandemir tenyearexperienceinmanagementofdiabeticketoacidosisandketosis140episodesatpediatricage
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