Both α2,3- and α2,6-linked sialic acids on O-linked glycoproteins act as functional receptors for porcine Sapovirus.

Both α2,3- and α2,6-linked sialic acids on O-linked glycoproteins act as functional receptors for porcine Sapovirus.

Sapovirus, a member of the Caliciviridae family, is an important cause of acute gastroenteritis in humans and pigs. Currently, the porcine sapovirus (PSaV) Cowden strain remains the only cultivable member of the Sapovirus genus. While some caliciviruses are known to utilize carbohydrate receptors fo...

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Bibliographic Details
Main Authors: Deok-Song Kim, Myra Hosmillo, Mia Madel Alfajaro, Ji-Yun Kim, Jun-Gyu Park, Kyu-Yeol Son, Eun-Hye Ryu, Frederic Sorgeloos, Hyung-Jun Kwon, Su-Jin Park, Woo Song Lee, Duck Cho, Joseph Kwon, Jong-Soon Choi, Mun-Il Kang, Ian Goodfellow, Kyoung-Oh Cho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004172&type=printable
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