A Rare Presentation of IgG4-Related Sinusitis With Chronic Nasal Obstruction and Headache: A Case Report and Literature Review
IgG4-related disease (IgG4-RD) is a systemic inflammatory condition characterized by tissue infiltration with IgG4-positive plasma cells and a tendency to form mass-like lesions in various organs. IgG4-related sinusitis, although a relatively rare manifestation of IgG4-RD, significantly impacts the...
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Korean Rhinologic Society
2024-11-01
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| Series: | Journal of Rhinology |
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| Online Access: | http://j-rhinology.org/upload/pdf/jr-2024-00025.pdf |
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| author | Dong Won Jung Ji Yun Choi |
| author_facet | Dong Won Jung Ji Yun Choi |
| author_sort | Dong Won Jung |
| collection | DOAJ |
| description | IgG4-related disease (IgG4-RD) is a systemic inflammatory condition characterized by tissue infiltration with IgG4-positive plasma cells and a tendency to form mass-like lesions in various organs. IgG4-related sinusitis, although a relatively rare manifestation of IgG4-RD, significantly impacts the paranasal sinuses. A 52-year-old man presented with persistent rhinorrhea, nasal obstruction, and headaches. He was diagnosed with IgG4-RD involving the bilateral nasal cavity, paranasal sinuses, submandibular glands, lacrimal glands, and parotid glands. We recently managed a case of IgG4-related sinusitis, which was successfully diagnosed and treated. This condition represents a distinct subset of chronic rhinosinusitis, with unique pathophysiological and clinical features. Accurate diagnosis and effective management of IgG4-related sinusitis require a high index of suspicion and a multidisciplinary approach. |
| format | Article |
| id | doaj-art-ca7c82eef2074a3c9455ab43ac3440db |
| institution | OA Journals |
| issn | 1229-1498 2384-4361 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Korean Rhinologic Society |
| record_format | Article |
| series | Journal of Rhinology |
| spelling | doaj-art-ca7c82eef2074a3c9455ab43ac3440db2025-08-20T01:59:17ZengKorean Rhinologic SocietyJournal of Rhinology1229-14982384-43612024-11-0131317918310.18787/jr.2024.00025827A Rare Presentation of IgG4-Related Sinusitis With Chronic Nasal Obstruction and Headache: A Case Report and Literature ReviewDong Won Jung0Ji Yun Choi Department of Otolaryngology-Head and Neck Surgery, Chosun University College of Medicine, Gwangju, Republic of KoreaIgG4-related disease (IgG4-RD) is a systemic inflammatory condition characterized by tissue infiltration with IgG4-positive plasma cells and a tendency to form mass-like lesions in various organs. IgG4-related sinusitis, although a relatively rare manifestation of IgG4-RD, significantly impacts the paranasal sinuses. A 52-year-old man presented with persistent rhinorrhea, nasal obstruction, and headaches. He was diagnosed with IgG4-RD involving the bilateral nasal cavity, paranasal sinuses, submandibular glands, lacrimal glands, and parotid glands. We recently managed a case of IgG4-related sinusitis, which was successfully diagnosed and treated. This condition represents a distinct subset of chronic rhinosinusitis, with unique pathophysiological and clinical features. Accurate diagnosis and effective management of IgG4-related sinusitis require a high index of suspicion and a multidisciplinary approach.http://j-rhinology.org/upload/pdf/jr-2024-00025.pdfigg4-related diseasesinusitisheadache |
| spellingShingle | Dong Won Jung Ji Yun Choi A Rare Presentation of IgG4-Related Sinusitis With Chronic Nasal Obstruction and Headache: A Case Report and Literature Review Journal of Rhinology igg4-related disease sinusitis headache |
| title | A Rare Presentation of IgG4-Related Sinusitis With Chronic Nasal Obstruction and Headache: A Case Report and Literature Review |
| title_full | A Rare Presentation of IgG4-Related Sinusitis With Chronic Nasal Obstruction and Headache: A Case Report and Literature Review |
| title_fullStr | A Rare Presentation of IgG4-Related Sinusitis With Chronic Nasal Obstruction and Headache: A Case Report and Literature Review |
| title_full_unstemmed | A Rare Presentation of IgG4-Related Sinusitis With Chronic Nasal Obstruction and Headache: A Case Report and Literature Review |
| title_short | A Rare Presentation of IgG4-Related Sinusitis With Chronic Nasal Obstruction and Headache: A Case Report and Literature Review |
| title_sort | rare presentation of igg4 related sinusitis with chronic nasal obstruction and headache a case report and literature review |
| topic | igg4-related disease sinusitis headache |
| url | http://j-rhinology.org/upload/pdf/jr-2024-00025.pdf |
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