A case of isolated meningitis caused by Bartonella henselae

Central nervous manifestations of bartonella infection are uncommon and can vary from encephalitis, meningitis, nerve palsy as well as ocular involvement. Most of these manifestations are described in immunocompromised individuals. We report a case of a previously healthy 42-year-old male who presen...

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Main Authors: Maria Del Pilar Morel Almonte, Jose Guillermo Castro
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:IDCases
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214250925000630
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author Maria Del Pilar Morel Almonte
Jose Guillermo Castro
author_facet Maria Del Pilar Morel Almonte
Jose Guillermo Castro
author_sort Maria Del Pilar Morel Almonte
collection DOAJ
description Central nervous manifestations of bartonella infection are uncommon and can vary from encephalitis, meningitis, nerve palsy as well as ocular involvement. Most of these manifestations are described in immunocompromised individuals. We report a case of a previously healthy 42-year-old male who presented to the hospital with 4-weeks of fever and headache and found with meningeal signs on physical exam. He reported been scratched by a stray cat at work some days before his symptoms started. He remained febrile in the hospital. Initial work up was unrevealing, but CSF analysis showed pleocytosis, elevated protein and low CSF glucose- plasma glucose ratio consistent with CNS bacterial infection. Blood and CSF cultures were negative. Bartonella henselae titers in serum were found to be elevated. No other source of infection was identified. Patient was diagnosed with isolated aseptic meningitis secondary to Bartonella henselae infection. Treatment with doxycycline and rifampin was started with good response and resolution of symptoms.
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spelling doaj-art-ca79b455dc5c4bf9a3e8c900e617d80a2025-08-20T02:31:11ZengElsevierIDCases2214-25092025-01-0140e0220810.1016/j.idcr.2025.e02208A case of isolated meningitis caused by Bartonella henselaeMaria Del Pilar Morel Almonte0Jose Guillermo Castro1Jackson Health System, Miami, FL, USA; Correspondence to: Jackson Health System, 1120 NW 14th street, Miami, FL 33136, USA.University of Miami, Miller School of Medicine, FL, USACentral nervous manifestations of bartonella infection are uncommon and can vary from encephalitis, meningitis, nerve palsy as well as ocular involvement. Most of these manifestations are described in immunocompromised individuals. We report a case of a previously healthy 42-year-old male who presented to the hospital with 4-weeks of fever and headache and found with meningeal signs on physical exam. He reported been scratched by a stray cat at work some days before his symptoms started. He remained febrile in the hospital. Initial work up was unrevealing, but CSF analysis showed pleocytosis, elevated protein and low CSF glucose- plasma glucose ratio consistent with CNS bacterial infection. Blood and CSF cultures were negative. Bartonella henselae titers in serum were found to be elevated. No other source of infection was identified. Patient was diagnosed with isolated aseptic meningitis secondary to Bartonella henselae infection. Treatment with doxycycline and rifampin was started with good response and resolution of symptoms.http://www.sciencedirect.com/science/article/pii/S2214250925000630Bartonella henselaeCat scratch disease (CSD)MeningitisFever of unkown origin (FUO)
spellingShingle Maria Del Pilar Morel Almonte
Jose Guillermo Castro
A case of isolated meningitis caused by Bartonella henselae
IDCases
Bartonella henselae
Cat scratch disease (CSD)
Meningitis
Fever of unkown origin (FUO)
title A case of isolated meningitis caused by Bartonella henselae
title_full A case of isolated meningitis caused by Bartonella henselae
title_fullStr A case of isolated meningitis caused by Bartonella henselae
title_full_unstemmed A case of isolated meningitis caused by Bartonella henselae
title_short A case of isolated meningitis caused by Bartonella henselae
title_sort case of isolated meningitis caused by bartonella henselae
topic Bartonella henselae
Cat scratch disease (CSD)
Meningitis
Fever of unkown origin (FUO)
url http://www.sciencedirect.com/science/article/pii/S2214250925000630
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