The Futile Creatine Cycle powers UCP1-independent thermogenesis in classical BAT

The Futile Creatine Cycle powers UCP1-independent thermogenesis in classical BAT

Abstract Classical brown adipose tissue (BAT) is traditionally viewed as relying exclusively on uncoupling protein 1 (UCP1) for thermogenesis via inducible proton leak. However, the physiological significance of UCP1-independent mechanisms linking substrate oxidation to ATP turnover in classical BAT...

Full description

Saved in:
Bibliographic Details
Main Authors: Jakub Bunk, Mohammed F. Hussain, Maria Delgado-Martin, Bozena Samborska, Mina Ersin, Abhirup Shaw, Janane F. Rahbani, Lawrence Kazak
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58294-4
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items