Effectiveness and Safety of Dose-Specific DOACs in Patients With Atrial Fibrillation: A Systematic Review and Network Meta-Analysis

Conclusions: This study found that all DOACs provided comparable or superior effectiveness and safety to warfarin. SD apixaban, SD edoxaban, and LD edoxaban achieved a favorable balance between preventing S/SE and MB risk.

Saved in:
Bibliographic Details
Main Authors: Sang-Hyeon Oh, Seunghyun Cheon, Seo-Yong Choi, Young Seo Kim, Han-Gon Choi, Jee-Eun Chung
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Cardiovascular Therapeutics
Online Access:http://dx.doi.org/10.1155/cdr/9923772
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850195138456846336
author Sang-Hyeon Oh
Seunghyun Cheon
Seo-Yong Choi
Young Seo Kim
Han-Gon Choi
Jee-Eun Chung
author_facet Sang-Hyeon Oh
Seunghyun Cheon
Seo-Yong Choi
Young Seo Kim
Han-Gon Choi
Jee-Eun Chung
author_sort Sang-Hyeon Oh
collection DOAJ
description Conclusions: This study found that all DOACs provided comparable or superior effectiveness and safety to warfarin. SD apixaban, SD edoxaban, and LD edoxaban achieved a favorable balance between preventing S/SE and MB risk.
format Article
id doaj-art-ca6571c4db974b93bc67f2bd51bd7491
institution OA Journals
issn 1755-5922
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series Cardiovascular Therapeutics
spelling doaj-art-ca6571c4db974b93bc67f2bd51bd74912025-08-20T02:13:49ZengWileyCardiovascular Therapeutics1755-59222025-01-01202510.1155/cdr/9923772Effectiveness and Safety of Dose-Specific DOACs in Patients With Atrial Fibrillation: A Systematic Review and Network Meta-AnalysisSang-Hyeon Oh0Seunghyun Cheon1Seo-Yong Choi2Young Seo Kim3Han-Gon Choi4Jee-Eun Chung5College of Pharmacy and Institute of Pharmaceutical Science and TechnologyCollege of Pharmacy and Institute of Pharmaceutical Science and TechnologyCollege of Pharmacy and Institute of Pharmaceutical Science and TechnologyDepartment of NeurologyCollege of Pharmacy and Institute of Pharmaceutical Science and TechnologyCollege of Pharmacy and Institute of Pharmaceutical Science and TechnologyConclusions: This study found that all DOACs provided comparable or superior effectiveness and safety to warfarin. SD apixaban, SD edoxaban, and LD edoxaban achieved a favorable balance between preventing S/SE and MB risk.http://dx.doi.org/10.1155/cdr/9923772
spellingShingle Sang-Hyeon Oh
Seunghyun Cheon
Seo-Yong Choi
Young Seo Kim
Han-Gon Choi
Jee-Eun Chung
Effectiveness and Safety of Dose-Specific DOACs in Patients With Atrial Fibrillation: A Systematic Review and Network Meta-Analysis
Cardiovascular Therapeutics
title Effectiveness and Safety of Dose-Specific DOACs in Patients With Atrial Fibrillation: A Systematic Review and Network Meta-Analysis
title_full Effectiveness and Safety of Dose-Specific DOACs in Patients With Atrial Fibrillation: A Systematic Review and Network Meta-Analysis
title_fullStr Effectiveness and Safety of Dose-Specific DOACs in Patients With Atrial Fibrillation: A Systematic Review and Network Meta-Analysis
title_full_unstemmed Effectiveness and Safety of Dose-Specific DOACs in Patients With Atrial Fibrillation: A Systematic Review and Network Meta-Analysis
title_short Effectiveness and Safety of Dose-Specific DOACs in Patients With Atrial Fibrillation: A Systematic Review and Network Meta-Analysis
title_sort effectiveness and safety of dose specific doacs in patients with atrial fibrillation a systematic review and network meta analysis
url http://dx.doi.org/10.1155/cdr/9923772
work_keys_str_mv AT sanghyeonoh effectivenessandsafetyofdosespecificdoacsinpatientswithatrialfibrillationasystematicreviewandnetworkmetaanalysis
AT seunghyuncheon effectivenessandsafetyofdosespecificdoacsinpatientswithatrialfibrillationasystematicreviewandnetworkmetaanalysis
AT seoyongchoi effectivenessandsafetyofdosespecificdoacsinpatientswithatrialfibrillationasystematicreviewandnetworkmetaanalysis
AT youngseokim effectivenessandsafetyofdosespecificdoacsinpatientswithatrialfibrillationasystematicreviewandnetworkmetaanalysis
AT hangonchoi effectivenessandsafetyofdosespecificdoacsinpatientswithatrialfibrillationasystematicreviewandnetworkmetaanalysis
AT jeeeunchung effectivenessandsafetyofdosespecificdoacsinpatientswithatrialfibrillationasystematicreviewandnetworkmetaanalysis