A Novel and Severe Clinical Picture Related to COVID-19: Multi-Inflammatory Syndrome in Children
Preliminary data have suggested that children have milder COVID-19 disease course compared to adults. However, pediatric cases with severe clinical findings caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) are being reported since April 2020. These children have been presented...
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| Format: | Article |
| Language: | English |
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Aydın Pediatric Society
2021-06-01
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| Series: | Trends in Pediatrics |
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| Online Access: | https://trendspediatrics.com/article/view/23 |
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| author | Fatih Haşlak Mehmet Yıldız Sezgin Şahin Amra Adrovic Yıldız Kenan Barut Özgür Kasapçopur |
| author_facet | Fatih Haşlak Mehmet Yıldız Sezgin Şahin Amra Adrovic Yıldız Kenan Barut Özgür Kasapçopur |
| author_sort | Fatih Haşlak |
| collection | DOAJ |
| description |
Preliminary data have suggested that children have milder COVID-19 disease course compared to adults. However, pediatric cases with severe clinical findings caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) are being reported since April 2020. These children have been presented with significant hyperinflammatory states resembling Kawasaki disease, toxic shock syndrome, and macrophage activation syndrome. However, they had several distinct features, as well. Therefore, this novel condition was considered a unique disease and named Multi-inflammatory syndrome in children (MIS-C). Thus, new concerns have been raised regarding the vulnerability of the children. However, it has been realized that this condition is extremely rare. Nonetheless, considering that it is a life-threatening disease and may cause devastating consequences, clinicians should be aware of MIS-C while evaluating children with persistent fever and history of COVID-19 contact or active infection.
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| format | Article |
| id | doaj-art-ca5fcd40b4474607b72d209168880f31 |
| institution | OA Journals |
| issn | 2792-0429 |
| language | English |
| publishDate | 2021-06-01 |
| publisher | Aydın Pediatric Society |
| record_format | Article |
| series | Trends in Pediatrics |
| spelling | doaj-art-ca5fcd40b4474607b72d209168880f312025-08-20T02:03:42ZengAydın Pediatric SocietyTrends in Pediatrics2792-04292021-06-012210.5222/TP.2021.75047A Novel and Severe Clinical Picture Related to COVID-19: Multi-Inflammatory Syndrome in ChildrenFatih Haşlak0https://orcid.org/0000-0002-6963-9668Mehmet Yıldız1https://orcid.org/0000-0002-7834-4909Sezgin Şahin2https://orcid.org/0000-0002-5365-3457Amra Adrovic Yıldız3https://orcid.org/0000-0002-2400-6955Kenan Barut4https://orcid.org/0000-0001-8459-2872Özgür Kasapçopur5https://orcid.org/0000-0002-1125-7720Istanbul University-Cerrahpasa Cerrahpasa Medical School, Department of Pediatric RheumatologyIstanbul University-Cerrahpasa Cerrahpasa Medical School, Department of Pediatric RheumatologyIstanbul University-Cerrahpasa Cerrahpasa Medical School, Department of Pediatric RheumatologyIstanbul University-Cerrahpasa Cerrahpasa Medical School, Department of Pediatric RheumatologyIstanbul University-Cerrahpasa Cerrahpasa Medical School, Department of Pediatric RheumatologyIstanbul University-Cerrahpasa Cerrahpasa Medical School, Department of Pediatric Rheumatology Preliminary data have suggested that children have milder COVID-19 disease course compared to adults. However, pediatric cases with severe clinical findings caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) are being reported since April 2020. These children have been presented with significant hyperinflammatory states resembling Kawasaki disease, toxic shock syndrome, and macrophage activation syndrome. However, they had several distinct features, as well. Therefore, this novel condition was considered a unique disease and named Multi-inflammatory syndrome in children (MIS-C). Thus, new concerns have been raised regarding the vulnerability of the children. However, it has been realized that this condition is extremely rare. Nonetheless, considering that it is a life-threatening disease and may cause devastating consequences, clinicians should be aware of MIS-C while evaluating children with persistent fever and history of COVID-19 contact or active infection. https://trendspediatrics.com/article/view/23SARS-CoV-2COVID-19MIS-CRheumatologyPediatric Intensive Care Unit. |
| spellingShingle | Fatih Haşlak Mehmet Yıldız Sezgin Şahin Amra Adrovic Yıldız Kenan Barut Özgür Kasapçopur A Novel and Severe Clinical Picture Related to COVID-19: Multi-Inflammatory Syndrome in Children Trends in Pediatrics SARS-CoV-2 COVID-19 MIS-C Rheumatology Pediatric Intensive Care Unit. |
| title | A Novel and Severe Clinical Picture Related to COVID-19: Multi-Inflammatory Syndrome in Children |
| title_full | A Novel and Severe Clinical Picture Related to COVID-19: Multi-Inflammatory Syndrome in Children |
| title_fullStr | A Novel and Severe Clinical Picture Related to COVID-19: Multi-Inflammatory Syndrome in Children |
| title_full_unstemmed | A Novel and Severe Clinical Picture Related to COVID-19: Multi-Inflammatory Syndrome in Children |
| title_short | A Novel and Severe Clinical Picture Related to COVID-19: Multi-Inflammatory Syndrome in Children |
| title_sort | novel and severe clinical picture related to covid 19 multi inflammatory syndrome in children |
| topic | SARS-CoV-2 COVID-19 MIS-C Rheumatology Pediatric Intensive Care Unit. |
| url | https://trendspediatrics.com/article/view/23 |
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