Unusual Late Onset of Parenchymal Neuro-Behçet Disease

Neuro-Behçet disease (NBD) is a multisystem inflammatory disorder characterized by oral lesions, genital lesions, uveitis, and neurological deficits. If left untreated, it may lead to worsening neurological function and can be fatal. Here we present a case of a 52-year-old woman who was diagnosed wi...

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Main Authors: Wai Wai Miller, Demetrios Konstas, Chetan Gandhy, Derrick Robertson
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2016/5720319
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author Wai Wai Miller
Demetrios Konstas
Chetan Gandhy
Derrick Robertson
author_facet Wai Wai Miller
Demetrios Konstas
Chetan Gandhy
Derrick Robertson
author_sort Wai Wai Miller
collection DOAJ
description Neuro-Behçet disease (NBD) is a multisystem inflammatory disorder characterized by oral lesions, genital lesions, uveitis, and neurological deficits. If left untreated, it may lead to worsening neurological function and can be fatal. Here we present a case of a 52-year-old woman who was diagnosed with Behçet disease (BD) as a teenager and had a relatively mild disease course. Decades later after her initial DB diagnosis, she presented to our hospital with a chief complaint of headache. She did not have focal neurological deficits or any active mucosal lesions. Upon further investigation, the patient was found to have multiple inflammatory changes on neuroimaging and abnormal cerebrospinal fluid (CSF), consistent with the diagnosis of NBD. She was treated with intravenous corticosteroid therapy and her symptoms resolved. Although our patient presented with minimal symptoms decades after her initial diagnosis, any neurological complaint warranted a thorough investigation for a proper diagnosis and treatment given the multisystem involvement of BD.
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spelling doaj-art-ca5d58098c034e7d9ee4a9d1d0fd623a2025-02-03T06:11:21ZengWileyCase Reports in Neurological Medicine2090-66682090-66762016-01-01201610.1155/2016/57203195720319Unusual Late Onset of Parenchymal Neuro-Behçet DiseaseWai Wai Miller0Demetrios Konstas1Chetan Gandhy2Derrick Robertson3Department of Neurology, University of South Florida, James A. Haley Veterans Hospital, 13000 Bruce B. Downs Boulevard VAH 127, Tampa, FL 33612, USADepartment of Neurology, University of South Florida, James A. Haley Veterans Hospital, 13000 Bruce B. Downs Boulevard VAH 127, Tampa, FL 33612, USADepartment of Neurology, University of South Florida, James A. Haley Veterans Hospital, 13000 Bruce B. Downs Boulevard VAH 127, Tampa, FL 33612, USADepartment of Neurology, University of South Florida, James A. Haley Veterans Hospital, 13000 Bruce B. Downs Boulevard VAH 127, Tampa, FL 33612, USANeuro-Behçet disease (NBD) is a multisystem inflammatory disorder characterized by oral lesions, genital lesions, uveitis, and neurological deficits. If left untreated, it may lead to worsening neurological function and can be fatal. Here we present a case of a 52-year-old woman who was diagnosed with Behçet disease (BD) as a teenager and had a relatively mild disease course. Decades later after her initial DB diagnosis, she presented to our hospital with a chief complaint of headache. She did not have focal neurological deficits or any active mucosal lesions. Upon further investigation, the patient was found to have multiple inflammatory changes on neuroimaging and abnormal cerebrospinal fluid (CSF), consistent with the diagnosis of NBD. She was treated with intravenous corticosteroid therapy and her symptoms resolved. Although our patient presented with minimal symptoms decades after her initial diagnosis, any neurological complaint warranted a thorough investigation for a proper diagnosis and treatment given the multisystem involvement of BD.http://dx.doi.org/10.1155/2016/5720319
spellingShingle Wai Wai Miller
Demetrios Konstas
Chetan Gandhy
Derrick Robertson
Unusual Late Onset of Parenchymal Neuro-Behçet Disease
Case Reports in Neurological Medicine
title Unusual Late Onset of Parenchymal Neuro-Behçet Disease
title_full Unusual Late Onset of Parenchymal Neuro-Behçet Disease
title_fullStr Unusual Late Onset of Parenchymal Neuro-Behçet Disease
title_full_unstemmed Unusual Late Onset of Parenchymal Neuro-Behçet Disease
title_short Unusual Late Onset of Parenchymal Neuro-Behçet Disease
title_sort unusual late onset of parenchymal neuro behcet disease
url http://dx.doi.org/10.1155/2016/5720319
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AT derrickrobertson unusuallateonsetofparenchymalneurobehcetdisease