Arthritis in Chronic Hepatitis C Infection: Is It Rheumatoid Like Arthritis or True Rheumatoid Arthritis?
Hepatitis C infection is often found in asymptomatic patients accidentaly during general check up, where there is increment levels of transaminases. Symptoms of hepatitis C infection include weakness, sleep disorders, nausea and so on. However, extrahepatic symptoms such as arthritis and myalgia are...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | Indonesian |
| Published: |
Department of Internal Medicine, Faculty of Medicine Universitas Indonesia
2020-03-01
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| Series: | Jurnal Penyakit Dalam Indonesia |
| Subjects: | |
| Online Access: | http://jurnalpenyakitdalam.ui.ac.id/index.php/jpdi/article/view/244/227 |
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| Summary: | Hepatitis C infection is often found in asymptomatic patients accidentaly during general check up, where there is increment levels of transaminases. Symptoms of hepatitis C infection include weakness, sleep disorders, nausea and so on. However, extrahepatic symptoms such as arthritis and myalgia are common. Arthritis is found in 2-20% of hepatitis C patients. As many as 2/3 of hepatitis C patients have arthritis resembling rheumatoid arthritis and the rest are oligoarthritis.
Studies showed that patients with chronic hepatitis C infection had twice the risk of developing rheumatoid arthritis. Hepatitis C patients with manifestations of arthritis are often misdiagnosed with rheumatoid arthritis. Because arthritis in hepatitis C patients also meets the criteria for diagnosis of rheumatoid arthritis according to ACR and EULAR 2010. Therefore, it is necessary to differentiate the causes of arthritis in patients with chronic hepatitis C, because the management of both diseases is very different.
This case report describes a 61-year-old woman with chronic hepatitis C infection and cirrhosis hepatis who had received hepatitis treatment and felt joint pain in the fingers of the left hand. Through physical examinations and anti-CCP investigations, rheumatoid factor, and CRP, it was found that patients suffered from rheumatoid arthritis. Patients get 1 x 250 mg chloroquine treatment and showed clinical improvement. |
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| ISSN: | 2406-8969 2549-0621 |