NeuroScale: evolutional scale-based protein language models enable prediction of neuropeptides

NeuroScale: evolutional scale-based protein language models enable prediction of neuropeptides

Abstract Background Neuropeptides (NPs) are critical signaling molecules involved in various physiological and behavioral processes, including development, metabolism, and memory. They function within both the nervous and endocrine systems and have emerged as promising therapeutic targets for a rang...

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Bibliographic Details
Main Authors: Hongqi Zhang, Shanghua Liu, Wei Su, Xueqin Xie, Junwen Yu, Fuying Dao, Mi Yang, Hao Lyu, Hao Lin
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Biology
Subjects:
Neuropeptide
Deep learning
ESM
GoogLeNet
Protein large language model
Online Access:https://doi.org/10.1186/s12915-025-02243-6
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