Pituitary adenoma apoplexy for ischemic infarction: three cases report and literature review
Objective To explore the pathogenesis, clinical manifestations, imaging and endocrine function characteristics, treatment methods, pathological characteristics and prognosis of pituitary adenoma apoplexy for ischemic infarction. Methods and Results All 3 patients with pituitary adenoma apoplexy for...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tianjin Huanhu Hospital
2025-04-01
|
| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
| Subjects: | |
| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/3014 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849309616213590016 |
|---|---|
| author | ZHAO Peng⁃fei WANG Jia⁃liang WANG Yan SUN Cheng⁃yuan LIU Hai⁃peng |
| author_facet | ZHAO Peng⁃fei WANG Jia⁃liang WANG Yan SUN Cheng⁃yuan LIU Hai⁃peng |
| author_sort | ZHAO Peng⁃fei |
| collection | DOAJ |
| description | Objective To explore the pathogenesis, clinical manifestations, imaging and endocrine function characteristics, treatment methods, pathological characteristics and prognosis of pituitary adenoma apoplexy for ischemic infarction. Methods and Results All 3 patients with pituitary adenoma apoplexy for ischemic infarction who were hospitalized in Affiliated Hospital of Hebei University from January 2021 to April 2022 were selected. All 3 patients presented with clinical manifestations such as headache, vision loss, cranial nerve palsy, and endocrine abnormalities. Preoperative endocrine examination indicated that one patient had decreased cortisol and prolactin levels. Preoperative MRI showed that all were large adenomas invading the cavernous sinus, hyperintensity on T1WI and T2WI, and uneven ring enhancement of the tumors. All 3 patients underwent endoscopic transsphenoidal resection of pituitary adenoma. Postoperative pathology confirmed pituitary adenoma with necrosis, all of which were coagulative necrosis. All 3 patients were finally diagnosed with pituitary adenoma apoplexy for ischemic infarction. Postoperatively, the clinical symptoms of all 3 patients improved significantly; one patient developed hypothyroidism and was treated with hormone supplementation. Conclusions The clinical features of pituitary adenoma apoplexy for ischemic infarction are relatively typical. Multidisciplinary cooperation should be carried out, and the best treatment plan should be formulated based on the clinical characteristics of the patients. |
| format | Article |
| id | doaj-art-ca5a6adf5ece4d9ca07a0fad0799a516 |
| institution | Kabale University |
| issn | 1672-6731 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Tianjin Huanhu Hospital |
| record_format | Article |
| series | Chinese Journal of Contemporary Neurology and Neurosurgery |
| spelling | doaj-art-ca5a6adf5ece4d9ca07a0fad0799a5162025-08-20T03:54:01ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312025-04-0125429630210.3969/j.issn.1672⁃6731.2025.04.006Pituitary adenoma apoplexy for ischemic infarction: three cases report and literature reviewZHAO Peng⁃fei0WANG Jia⁃liang1WANG Yan2SUN Cheng⁃yuan3LIU Hai⁃peng4Department of Neurosurgery, Affiliated Hospital of Hebei University, Baoding 071000, Hebei, ChinaDepartment of Neurosurgery, Affiliated Hospital of Hebei University, Baoding 071000, Hebei, ChinaDepartment of Neurosurgery, Affiliated Hospital of Hebei University, Baoding 071000, Hebei, ChinaDepartment of Neurosurgery, Affiliated Hospital of Hebei University, Baoding 071000, Hebei, ChinaDepartment of Neurosurgery, Affiliated Hospital of Hebei University, Baoding 071000, Hebei, ChinaObjective To explore the pathogenesis, clinical manifestations, imaging and endocrine function characteristics, treatment methods, pathological characteristics and prognosis of pituitary adenoma apoplexy for ischemic infarction. Methods and Results All 3 patients with pituitary adenoma apoplexy for ischemic infarction who were hospitalized in Affiliated Hospital of Hebei University from January 2021 to April 2022 were selected. All 3 patients presented with clinical manifestations such as headache, vision loss, cranial nerve palsy, and endocrine abnormalities. Preoperative endocrine examination indicated that one patient had decreased cortisol and prolactin levels. Preoperative MRI showed that all were large adenomas invading the cavernous sinus, hyperintensity on T1WI and T2WI, and uneven ring enhancement of the tumors. All 3 patients underwent endoscopic transsphenoidal resection of pituitary adenoma. Postoperative pathology confirmed pituitary adenoma with necrosis, all of which were coagulative necrosis. All 3 patients were finally diagnosed with pituitary adenoma apoplexy for ischemic infarction. Postoperatively, the clinical symptoms of all 3 patients improved significantly; one patient developed hypothyroidism and was treated with hormone supplementation. Conclusions The clinical features of pituitary adenoma apoplexy for ischemic infarction are relatively typical. Multidisciplinary cooperation should be carried out, and the best treatment plan should be formulated based on the clinical characteristics of the patients.http://www.cjcnn.org/index.php/cjcnn/article/view/3014pituitary neoplasmsadenomaischemic strokepituitary hormonesmagnetic resonance imagingpathology |
| spellingShingle | ZHAO Peng⁃fei WANG Jia⁃liang WANG Yan SUN Cheng⁃yuan LIU Hai⁃peng Pituitary adenoma apoplexy for ischemic infarction: three cases report and literature review Chinese Journal of Contemporary Neurology and Neurosurgery pituitary neoplasms adenoma ischemic stroke pituitary hormones magnetic resonance imaging pathology |
| title | Pituitary adenoma apoplexy for ischemic infarction: three cases report and literature review |
| title_full | Pituitary adenoma apoplexy for ischemic infarction: three cases report and literature review |
| title_fullStr | Pituitary adenoma apoplexy for ischemic infarction: three cases report and literature review |
| title_full_unstemmed | Pituitary adenoma apoplexy for ischemic infarction: three cases report and literature review |
| title_short | Pituitary adenoma apoplexy for ischemic infarction: three cases report and literature review |
| title_sort | pituitary adenoma apoplexy for ischemic infarction three cases report and literature review |
| topic | pituitary neoplasms adenoma ischemic stroke pituitary hormones magnetic resonance imaging pathology |
| url | http://www.cjcnn.org/index.php/cjcnn/article/view/3014 |
| work_keys_str_mv | AT zhaopengfei pituitaryadenomaapoplexyforischemicinfarctionthreecasesreportandliteraturereview AT wangjialiang pituitaryadenomaapoplexyforischemicinfarctionthreecasesreportandliteraturereview AT wangyan pituitaryadenomaapoplexyforischemicinfarctionthreecasesreportandliteraturereview AT sunchengyuan pituitaryadenomaapoplexyforischemicinfarctionthreecasesreportandliteraturereview AT liuhaipeng pituitaryadenomaapoplexyforischemicinfarctionthreecasesreportandliteraturereview |