Phylogenetic Analysis of Streptomyces spp. Isolated from Soil Samples in Sulaimani Governorate

Streptomyces species have been an important source of bioactive secondary metabolites and clinically useful for antibiotic production, including fosfomycin, daptomycin, oxytetracycline, streptomycin, and chloramphenicol. The main objective of this study was to isolate actinomycetes, especially Strep...

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Main Authors: Syamand A. Qadir, Miran H. Qadir, Osama H. Shareef, Aryan M. Faraj
Format: Article
Language:English
Published: Erbil Polytechnic University 2020-06-01
Series:Polytechnic Journal
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Online Access:https://polytechnic-journal.epu.edu.iq/home/vol10/iss1/4
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author Syamand A. Qadir
Miran H. Qadir
Osama H. Shareef
Aryan M. Faraj
author_facet Syamand A. Qadir
Miran H. Qadir
Osama H. Shareef
Aryan M. Faraj
author_sort Syamand A. Qadir
collection DOAJ
description Streptomyces species have been an important source of bioactive secondary metabolites and clinically useful for antibiotic production, including fosfomycin, daptomycin, oxytetracycline, streptomycin, and chloramphenicol. The main objective of this study was to isolate actinomycetes, especially Streptomyces from 8 soil samples that collected from two different places, which are districts in Sulaimani governorate, Kurdistan Region of Iraq. Totally, 30 diagnostic tests were carried out for representative of isolated Streptomyces depending on the color groups. The 16Sr DNA gene was sequenced, for ten isolated test strains were amplified with 2 universal primers after extraction of genomic DNA, only 8 of them were successfully sequenced. Phylogenetic analysis of 8 test strains carried out using base sequences of 16Sr DNA genes in the core genome. Four of isolated test strains were identified as a Streptomyces fulvissimus, and others were nominated as a Streptomyces anulatus. The obtained sequence data were compared with the sequence data of the closest related species in the international databases using EzTaxon Server program and (%) similarities were determined. Finally, phylogenetic analysis indicated that isolated test strains were nominated as (H001, H002, H003, and H004), which recognized members of the S. anulatus and the similarity with their type strain is 99.93%. Whereas, other four isolated test strains, including D001, D002, D003, and D004 recognized as members of the S. fulvissimus and similarity with their type strain is 100%.
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spelling doaj-art-ca51cebde05244ddb51fd1398b2a282c2025-08-20T03:05:06ZengErbil Polytechnic UniversityPolytechnic Journal2707-77992020-06-011011824https://doi.org/10.25156/ptj.v10n1y2020.pp18-24Phylogenetic Analysis of Streptomyces spp. Isolated from Soil Samples in Sulaimani GovernorateSyamand A. Qadir0Miran H. Qadir1Osama H. Shareef2Aryan M. Faraj3Department of Medical Laboratory Science, Technical College of Applied Sciences, Sulaimani Polytechnic University, Sulaymaniyah, Kurdistan Region, Iraq, Department of Horticulture, Collage of Agricultural Engineering Sciences, University of Raparin, Sulaymaniyah, Kurdistan Region, IraqDepartment of Medical Laboratory Science, Technical College of Applied Sciences, Sulaimani Polytechnic University, Sulaymaniyah, Kurdistan Region, Iraq, Department of Medical Laboratory Science, Technical College of Applied Sciences, Sulaimani Polytechnic University, Sulaymaniyah, Kurdistan Region, Iraq, Streptomyces species have been an important source of bioactive secondary metabolites and clinically useful for antibiotic production, including fosfomycin, daptomycin, oxytetracycline, streptomycin, and chloramphenicol. The main objective of this study was to isolate actinomycetes, especially Streptomyces from 8 soil samples that collected from two different places, which are districts in Sulaimani governorate, Kurdistan Region of Iraq. Totally, 30 diagnostic tests were carried out for representative of isolated Streptomyces depending on the color groups. The 16Sr DNA gene was sequenced, for ten isolated test strains were amplified with 2 universal primers after extraction of genomic DNA, only 8 of them were successfully sequenced. Phylogenetic analysis of 8 test strains carried out using base sequences of 16Sr DNA genes in the core genome. Four of isolated test strains were identified as a Streptomyces fulvissimus, and others were nominated as a Streptomyces anulatus. The obtained sequence data were compared with the sequence data of the closest related species in the international databases using EzTaxon Server program and (%) similarities were determined. Finally, phylogenetic analysis indicated that isolated test strains were nominated as (H001, H002, H003, and H004), which recognized members of the S. anulatus and the similarity with their type strain is 99.93%. Whereas, other four isolated test strains, including D001, D002, D003, and D004 recognized as members of the S. fulvissimus and similarity with their type strain is 100%.https://polytechnic-journal.epu.edu.iq/home/vol10/iss1/4actinobacteria;streptomyces;antibiotic;16sr dna and diaminopimelic acid;soil
spellingShingle Syamand A. Qadir
Miran H. Qadir
Osama H. Shareef
Aryan M. Faraj
Phylogenetic Analysis of Streptomyces spp. Isolated from Soil Samples in Sulaimani Governorate
Polytechnic Journal
actinobacteria;
streptomyces;
antibiotic;
16sr dna and diaminopimelic acid;
soil
title Phylogenetic Analysis of Streptomyces spp. Isolated from Soil Samples in Sulaimani Governorate
title_full Phylogenetic Analysis of Streptomyces spp. Isolated from Soil Samples in Sulaimani Governorate
title_fullStr Phylogenetic Analysis of Streptomyces spp. Isolated from Soil Samples in Sulaimani Governorate
title_full_unstemmed Phylogenetic Analysis of Streptomyces spp. Isolated from Soil Samples in Sulaimani Governorate
title_short Phylogenetic Analysis of Streptomyces spp. Isolated from Soil Samples in Sulaimani Governorate
title_sort phylogenetic analysis of streptomyces spp isolated from soil samples in sulaimani governorate
topic actinobacteria;
streptomyces;
antibiotic;
16sr dna and diaminopimelic acid;
soil
url https://polytechnic-journal.epu.edu.iq/home/vol10/iss1/4
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AT osamahshareef phylogeneticanalysisofstreptomycessppisolatedfromsoilsamplesinsulaimanigovernorate
AT aryanmfaraj phylogeneticanalysisofstreptomycessppisolatedfromsoilsamplesinsulaimanigovernorate