Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry
Synthetic anabolic hormones, which may pose a potential risk to human health, should not be used in fattening food-producing animals. Because of the hormonal effects they cause, growth-promoting compounds are banned by legislation in the EU for use in animal husbandry. Consequently, all EU member st...
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Language: | English |
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2024-12-01
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Series: | Journal of Veterinary Research |
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Online Access: | https://doi.org/10.2478/jvetres-2024-0070 |
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author | Matraszek-Żuchowska Iwona Kłopot Alicja Grzelak Justyna Zdonek Paulina |
author_facet | Matraszek-Żuchowska Iwona Kłopot Alicja Grzelak Justyna Zdonek Paulina |
author_sort | Matraszek-Żuchowska Iwona |
collection | DOAJ |
description | Synthetic anabolic hormones, which may pose a potential risk to human health, should not be used in fattening food-producing animals. Because of the hormonal effects they cause, growth-promoting compounds are banned by legislation in the EU for use in animal husbandry. Consequently, all EU member states are required to conduct monitoring tests on the content and residues of these compounds in prescribed biological matrices to ensure the safety of food consumers. The aim of this research was to develop a liquid chromatography–tandem mass spectrometry method for the detection of the residue of one such anabolic hormone, clostebol in food animal urine. |
format | Article |
id | doaj-art-ca4db92b46744666ac8a1cc0b8aa1ae0 |
institution | Kabale University |
issn | 2450-8608 |
language | English |
publishDate | 2024-12-01 |
publisher | Sciendo |
record_format | Article |
series | Journal of Veterinary Research |
spelling | doaj-art-ca4db92b46744666ac8a1cc0b8aa1ae02025-01-07T07:56:37ZengSciendoJournal of Veterinary Research2450-86082024-12-0168461162110.2478/jvetres-2024-0070Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometryMatraszek-Żuchowska Iwona0Kłopot Alicja1Grzelak Justyna2Zdonek Paulina3Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100Puławy, PolandDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100Puławy, PolandDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100Puławy, PolandDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100Puławy, PolandSynthetic anabolic hormones, which may pose a potential risk to human health, should not be used in fattening food-producing animals. Because of the hormonal effects they cause, growth-promoting compounds are banned by legislation in the EU for use in animal husbandry. Consequently, all EU member states are required to conduct monitoring tests on the content and residues of these compounds in prescribed biological matrices to ensure the safety of food consumers. The aim of this research was to develop a liquid chromatography–tandem mass spectrometry method for the detection of the residue of one such anabolic hormone, clostebol in food animal urine.https://doi.org/10.2478/jvetres-2024-0070urineclostebolhormone residuelc-ms/ms |
spellingShingle | Matraszek-Żuchowska Iwona Kłopot Alicja Grzelak Justyna Zdonek Paulina Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry Journal of Veterinary Research urine clostebol hormone residue lc-ms/ms |
title | Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry |
title_full | Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry |
title_fullStr | Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry |
title_full_unstemmed | Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry |
title_short | Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry |
title_sort | determination of clostebol residues in the urine of slaughter animals using liquid chromatography tandem mass spectrometry |
topic | urine clostebol hormone residue lc-ms/ms |
url | https://doi.org/10.2478/jvetres-2024-0070 |
work_keys_str_mv | AT matraszekzuchowskaiwona determinationofclostebolresiduesintheurineofslaughteranimalsusingliquidchromatographytandemmassspectrometry AT kłopotalicja determinationofclostebolresiduesintheurineofslaughteranimalsusingliquidchromatographytandemmassspectrometry AT grzelakjustyna determinationofclostebolresiduesintheurineofslaughteranimalsusingliquidchromatographytandemmassspectrometry AT zdonekpaulina determinationofclostebolresiduesintheurineofslaughteranimalsusingliquidchromatographytandemmassspectrometry |