Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry

Synthetic anabolic hormones, which may pose a potential risk to human health, should not be used in fattening food-producing animals. Because of the hormonal effects they cause, growth-promoting compounds are banned by legislation in the EU for use in animal husbandry. Consequently, all EU member st...

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Main Authors: Matraszek-Żuchowska Iwona, Kłopot Alicja, Grzelak Justyna, Zdonek Paulina
Format: Article
Language:English
Published: Sciendo 2024-12-01
Series:Journal of Veterinary Research
Subjects:
Online Access:https://doi.org/10.2478/jvetres-2024-0070
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author Matraszek-Żuchowska Iwona
Kłopot Alicja
Grzelak Justyna
Zdonek Paulina
author_facet Matraszek-Żuchowska Iwona
Kłopot Alicja
Grzelak Justyna
Zdonek Paulina
author_sort Matraszek-Żuchowska Iwona
collection DOAJ
description Synthetic anabolic hormones, which may pose a potential risk to human health, should not be used in fattening food-producing animals. Because of the hormonal effects they cause, growth-promoting compounds are banned by legislation in the EU for use in animal husbandry. Consequently, all EU member states are required to conduct monitoring tests on the content and residues of these compounds in prescribed biological matrices to ensure the safety of food consumers. The aim of this research was to develop a liquid chromatography–tandem mass spectrometry method for the detection of the residue of one such anabolic hormone, clostebol in food animal urine.
format Article
id doaj-art-ca4db92b46744666ac8a1cc0b8aa1ae0
institution Kabale University
issn 2450-8608
language English
publishDate 2024-12-01
publisher Sciendo
record_format Article
series Journal of Veterinary Research
spelling doaj-art-ca4db92b46744666ac8a1cc0b8aa1ae02025-01-07T07:56:37ZengSciendoJournal of Veterinary Research2450-86082024-12-0168461162110.2478/jvetres-2024-0070Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometryMatraszek-Żuchowska Iwona0Kłopot Alicja1Grzelak Justyna2Zdonek Paulina3Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100Puławy, PolandDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100Puławy, PolandDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100Puławy, PolandDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100Puławy, PolandSynthetic anabolic hormones, which may pose a potential risk to human health, should not be used in fattening food-producing animals. Because of the hormonal effects they cause, growth-promoting compounds are banned by legislation in the EU for use in animal husbandry. Consequently, all EU member states are required to conduct monitoring tests on the content and residues of these compounds in prescribed biological matrices to ensure the safety of food consumers. The aim of this research was to develop a liquid chromatography–tandem mass spectrometry method for the detection of the residue of one such anabolic hormone, clostebol in food animal urine.https://doi.org/10.2478/jvetres-2024-0070urineclostebolhormone residuelc-ms/ms
spellingShingle Matraszek-Żuchowska Iwona
Kłopot Alicja
Grzelak Justyna
Zdonek Paulina
Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry
Journal of Veterinary Research
urine
clostebol
hormone residue
lc-ms/ms
title Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry
title_full Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry
title_fullStr Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry
title_full_unstemmed Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry
title_short Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry
title_sort determination of clostebol residues in the urine of slaughter animals using liquid chromatography tandem mass spectrometry
topic urine
clostebol
hormone residue
lc-ms/ms
url https://doi.org/10.2478/jvetres-2024-0070
work_keys_str_mv AT matraszekzuchowskaiwona determinationofclostebolresiduesintheurineofslaughteranimalsusingliquidchromatographytandemmassspectrometry
AT kłopotalicja determinationofclostebolresiduesintheurineofslaughteranimalsusingliquidchromatographytandemmassspectrometry
AT grzelakjustyna determinationofclostebolresiduesintheurineofslaughteranimalsusingliquidchromatographytandemmassspectrometry
AT zdonekpaulina determinationofclostebolresiduesintheurineofslaughteranimalsusingliquidchromatographytandemmassspectrometry