Predator scent stress reduces oxycodone self-administration and the nucleus accumbens dopamine response to oxycodone in female rats

Predator scent stress reduces oxycodone self-administration and the nucleus accumbens dopamine response to oxycodone in female rats

Post-traumatic stress disorder (PTSD) develops in a sub-population of people exposed to trauma and is highly comorbid with opioid use disorder (OUD). The neurobiology of comorbid PTSD+OUD, especially with respect to sex differences, is poorly understood. Here we investigated the sex-specific effects...

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Bibliographic Details
Main Authors: Courtney S. Wilkinson, Siya Bhutani, Wonn Pyon, Marek Schwendt, Lori A. Knackstedt
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Addiction Neuroscience
Subjects:
Anhedonia
Substance use disorder
Addiction
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772392525000161
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