New insights into pathogenisis and therapies of P2X7R in Parkinson’s disease
Abstract Parkinson’s disease (PD), a prevalent neurodegenerative disorder, is linked to genetics and environment, but its mechanisms remain unclear. Emerging evidence connects purinergic signaling-particularly ATP-sensitive P2X7 receptor (P2X7R)-to PD. P2X7R expression is elevated in PD patients, an...
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| Main Authors: | Shizhuang Wei, Xiaoyu Song, Yakui Mou, Ting Yang, Yao Wang, Hanrui Wang, Chao Ren, Xicheng Song |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | npj Parkinson's Disease |
| Online Access: | https://doi.org/10.1038/s41531-025-00980-7 |
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