Two-dimensional speckle tracking echocardiography and stress computed tomography myocardial perfusion: potential for early imaging of asymptomatic patients with myocardial bridges
Aim. To evaluate the effectiveness of left ventricular (LV) peak global longitudinal strain and potential of computed tomography myocardial perfusion (CT perfusion) for the early diagnosis of asymptomatic patients with myocardial bridges (MBs).Material and methods. Forty patients were examined (20 w...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«FIRMA «SILICEA» LLC
2024-08-01
|
| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/5889 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849340940080119808 |
|---|---|
| author | N. T. Mirzoev K. S. Shulenin G. G. Kutelev T. G. Tedeev D. V. Cherkashin V. V. Ivanov |
| author_facet | N. T. Mirzoev K. S. Shulenin G. G. Kutelev T. G. Tedeev D. V. Cherkashin V. V. Ivanov |
| author_sort | N. T. Mirzoev |
| collection | DOAJ |
| description | Aim. To evaluate the effectiveness of left ventricular (LV) peak global longitudinal strain and potential of computed tomography myocardial perfusion (CT perfusion) for the early diagnosis of asymptomatic patients with myocardial bridges (MBs).Material and methods. Forty patients were examined (20 with asymptomatic MBs in the area of the left anterior descending (LAD) artery and 20 without MBs) at the S. M. Kirov Military Medical Academy in the period from 2021 to 2023. The patients were divided into 2 equal groups consisting of 20 people (10 with MBs — the main group; 10 without MBs — the comparison group), one of which underwent speckle tracking echocardiography (STE), and the other — stress CT perfusion performed (adenosine triphosphate 160 mg/kg). The results were assessed in accordance with the 17-segment classification of LV proposed by the American Heart Association (2002).Results. When performing STE, 5 (50%) patients with MBs showed a decrease in LV local strain in the segments, the blood supply of which comes from the LAD artery and its branches, while in the comparison group — 1 (10%) (x2=5; p=0,025). When assessing the global longitudinal peak strain (GLPS), a significant difference was revealed among the study groups, amounting to -20,9±1,5% in patients with MBs and -22,1±0,9% in those without MBs (p=0,04). Using ROC analysis, the effectiveness of GLPS in prediction of asymptomatic MBs was calculated as follows: AUC=0,93 (95% confidence interval: 0,819-1,0; p=0,001), the cut-off point — -20,55% (sensitivity 80%, specificity 100%). According to CT perfusion data, impaired myocardial blood supply in the group of asymptomatic patients with MBs was noted in 6 (60%) cases, and in the comparison group — 2 (20%) (x2=9,8; p=0,002).Conclusion. Imaging of initial LV changes according to two-dimensional STE and detection of coronary circulatory disorders according to CT myocardial perfusion in asymptomatic patients with MBs makes it possible to timely suspect intramyocardial course of the coronary artery, as well as to consider further management tactics and carry out early prevention of possible cardiovascular events. |
| format | Article |
| id | doaj-art-ca427f8c9f164a37b3bed4e008f89c95 |
| institution | Kabale University |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| publishDate | 2024-08-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj-art-ca427f8c9f164a37b3bed4e008f89c952025-08-20T03:43:46Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202024-08-0129710.15829/1560-4071-2024-58894156Two-dimensional speckle tracking echocardiography and stress computed tomography myocardial perfusion: potential for early imaging of asymptomatic patients with myocardial bridgesN. T. Mirzoev0K. S. Shulenin1G. G. Kutelev2T. G. Tedeev3D. V. Cherkashin4V. V. Ivanov5Clinical Navy Hospital № 1469S.M. Kirov Military Medical AcademyS.M. Kirov Military Medical AcademyS.M. Kirov Military Medical AcademyS.M. Kirov Military Medical AcademyS.M. Kirov Military Medical AcademyAim. To evaluate the effectiveness of left ventricular (LV) peak global longitudinal strain and potential of computed tomography myocardial perfusion (CT perfusion) for the early diagnosis of asymptomatic patients with myocardial bridges (MBs).Material and methods. Forty patients were examined (20 with asymptomatic MBs in the area of the left anterior descending (LAD) artery and 20 without MBs) at the S. M. Kirov Military Medical Academy in the period from 2021 to 2023. The patients were divided into 2 equal groups consisting of 20 people (10 with MBs — the main group; 10 without MBs — the comparison group), one of which underwent speckle tracking echocardiography (STE), and the other — stress CT perfusion performed (adenosine triphosphate 160 mg/kg). The results were assessed in accordance with the 17-segment classification of LV proposed by the American Heart Association (2002).Results. When performing STE, 5 (50%) patients with MBs showed a decrease in LV local strain in the segments, the blood supply of which comes from the LAD artery and its branches, while in the comparison group — 1 (10%) (x2=5; p=0,025). When assessing the global longitudinal peak strain (GLPS), a significant difference was revealed among the study groups, amounting to -20,9±1,5% in patients with MBs and -22,1±0,9% in those without MBs (p=0,04). Using ROC analysis, the effectiveness of GLPS in prediction of asymptomatic MBs was calculated as follows: AUC=0,93 (95% confidence interval: 0,819-1,0; p=0,001), the cut-off point — -20,55% (sensitivity 80%, specificity 100%). According to CT perfusion data, impaired myocardial blood supply in the group of asymptomatic patients with MBs was noted in 6 (60%) cases, and in the comparison group — 2 (20%) (x2=9,8; p=0,002).Conclusion. Imaging of initial LV changes according to two-dimensional STE and detection of coronary circulatory disorders according to CT myocardial perfusion in asymptomatic patients with MBs makes it possible to timely suspect intramyocardial course of the coronary artery, as well as to consider further management tactics and carry out early prevention of possible cardiovascular events.https://russjcardiol.elpub.ru/jour/article/view/5889myocardial bridgedevelopmental anomalycomputed tomographymyocardial perfusionechocardiographyspeckle tracking |
| spellingShingle | N. T. Mirzoev K. S. Shulenin G. G. Kutelev T. G. Tedeev D. V. Cherkashin V. V. Ivanov Two-dimensional speckle tracking echocardiography and stress computed tomography myocardial perfusion: potential for early imaging of asymptomatic patients with myocardial bridges Российский кардиологический журнал myocardial bridge developmental anomaly computed tomography myocardial perfusion echocardiography speckle tracking |
| title | Two-dimensional speckle tracking echocardiography and stress computed tomography myocardial perfusion: potential for early imaging of asymptomatic patients with myocardial bridges |
| title_full | Two-dimensional speckle tracking echocardiography and stress computed tomography myocardial perfusion: potential for early imaging of asymptomatic patients with myocardial bridges |
| title_fullStr | Two-dimensional speckle tracking echocardiography and stress computed tomography myocardial perfusion: potential for early imaging of asymptomatic patients with myocardial bridges |
| title_full_unstemmed | Two-dimensional speckle tracking echocardiography and stress computed tomography myocardial perfusion: potential for early imaging of asymptomatic patients with myocardial bridges |
| title_short | Two-dimensional speckle tracking echocardiography and stress computed tomography myocardial perfusion: potential for early imaging of asymptomatic patients with myocardial bridges |
| title_sort | two dimensional speckle tracking echocardiography and stress computed tomography myocardial perfusion potential for early imaging of asymptomatic patients with myocardial bridges |
| topic | myocardial bridge developmental anomaly computed tomography myocardial perfusion echocardiography speckle tracking |
| url | https://russjcardiol.elpub.ru/jour/article/view/5889 |
| work_keys_str_mv | AT ntmirzoev twodimensionalspeckletrackingechocardiographyandstresscomputedtomographymyocardialperfusionpotentialforearlyimagingofasymptomaticpatientswithmyocardialbridges AT ksshulenin twodimensionalspeckletrackingechocardiographyandstresscomputedtomographymyocardialperfusionpotentialforearlyimagingofasymptomaticpatientswithmyocardialbridges AT ggkutelev twodimensionalspeckletrackingechocardiographyandstresscomputedtomographymyocardialperfusionpotentialforearlyimagingofasymptomaticpatientswithmyocardialbridges AT tgtedeev twodimensionalspeckletrackingechocardiographyandstresscomputedtomographymyocardialperfusionpotentialforearlyimagingofasymptomaticpatientswithmyocardialbridges AT dvcherkashin twodimensionalspeckletrackingechocardiographyandstresscomputedtomographymyocardialperfusionpotentialforearlyimagingofasymptomaticpatientswithmyocardialbridges AT vvivanov twodimensionalspeckletrackingechocardiographyandstresscomputedtomographymyocardialperfusionpotentialforearlyimagingofasymptomaticpatientswithmyocardialbridges |