In-silico molecular analysis and blocking of the viral G protein of Nipah virus interacting with ephrin B2 and B3 receptor by using peptide mass fingerprinting

In-silico molecular analysis and blocking of the viral G protein of Nipah virus interacting with ephrin B2 and B3 receptor by using peptide mass fingerprinting

IntroductionThe Nipah virus (NiV), a zoonotic paramyxovirus closely related to the Hendra virus, poses a significant global health threat due to its high mortality rate, zoonotic nature, and recurring outbreaks primarily in Malaysia, Bangladesh, and India. Infection with NiV leads to severe encephal...

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Main Authors: Ayesha Sajjad, Ihteshamul Haq, Rabia Syed, Faheem Anwar, Muhammad Hamza, Muhammad Musharaf, Tehmina Kiani, Faisal Nouroz
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Bioinformatics
Subjects:
peptide mass fingerprinting
paramyxovirus
ephrin B2 and B3 receptor
viral g protein
nipah virus (NiV)
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2025.1526566/full
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