Comparative evaluation of free available chlorine in sodium hypochlorite solutions admixed with novel chelating agents
Aim: This study evaluated the effects of ethylenediaminetetraacetic acid (EDTA), etidronic acid (HEBP), peracetic acid (PAA), phytic acid (IP6), and glycolic acid (AHA) on the free available chlorine (FAC) content of sodium hypochlorite (NaOCl) solution when mixed in varying proportions. Methods: Tw...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-04-01
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| Series: | Endodontology |
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| Online Access: | https://journals.lww.com/10.4103/endo.endo_219_24 |
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| _version_ | 1849426626392096768 |
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| author | Somya Tyagi Sonali Taneja Kandasamy Nagarajan Divya Chowdhary |
| author_facet | Somya Tyagi Sonali Taneja Kandasamy Nagarajan Divya Chowdhary |
| author_sort | Somya Tyagi |
| collection | DOAJ |
| description | Aim:
This study evaluated the effects of ethylenediaminetetraacetic acid (EDTA), etidronic acid (HEBP), peracetic acid (PAA), phytic acid (IP6), and glycolic acid (AHA) on the free available chlorine (FAC) content of sodium hypochlorite (NaOCl) solution when mixed in varying proportions.
Methods:
Twenty-five milliliter aliquots of 5.25% NaOCl were admixed in ratios of 90:10, 80:20, and 50:50 with secondary irrigation solutions: (a) 17% EDTA, (b) 9% HEBP, (c) 1% PAA, (d) 1% IP6, and (e) 10% AHA. Iodometric titration was done to evaluate the change in FAC. Statistical differences between means were determined using a post hoc Tukey’s analysis test after an analysis of variance.
Results:
On titration, the mean FAC value of NaOCl at baseline was 2.02 g%. On mixing NaOCl with EDTA and HEBP, the FAC decreased in all three proportions. On mixing NaOCl and PAA, the FAC increased on increasing dilution in all three proportions. On mixing NaOCl and IP6, the FAC decreased only in 80:20 dilutions. On mixing NaOCl and AHA, the FAC increased on increasing dilution in all three proportions.
Conclusion:
The FAC on the combination of NaOCl with AHA, PAA, and IP6 remained unaltered or decreased marginally, suggesting that the antimicrobial properties of NaOCl might be preserved. |
| format | Article |
| id | doaj-art-ca3afb2c778345c99257fc5876d9740c |
| institution | Kabale University |
| issn | 0970-7212 2543-0831 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Endodontology |
| spelling | doaj-art-ca3afb2c778345c99257fc5876d9740c2025-08-20T03:29:18ZengWolters Kluwer Medknow PublicationsEndodontology0970-72122543-08312025-04-0137218819310.4103/endo.endo_219_24Comparative evaluation of free available chlorine in sodium hypochlorite solutions admixed with novel chelating agentsSomya TyagiSonali TanejaKandasamy NagarajanDivya ChowdharyAim: This study evaluated the effects of ethylenediaminetetraacetic acid (EDTA), etidronic acid (HEBP), peracetic acid (PAA), phytic acid (IP6), and glycolic acid (AHA) on the free available chlorine (FAC) content of sodium hypochlorite (NaOCl) solution when mixed in varying proportions. Methods: Twenty-five milliliter aliquots of 5.25% NaOCl were admixed in ratios of 90:10, 80:20, and 50:50 with secondary irrigation solutions: (a) 17% EDTA, (b) 9% HEBP, (c) 1% PAA, (d) 1% IP6, and (e) 10% AHA. Iodometric titration was done to evaluate the change in FAC. Statistical differences between means were determined using a post hoc Tukey’s analysis test after an analysis of variance. Results: On titration, the mean FAC value of NaOCl at baseline was 2.02 g%. On mixing NaOCl with EDTA and HEBP, the FAC decreased in all three proportions. On mixing NaOCl and PAA, the FAC increased on increasing dilution in all three proportions. On mixing NaOCl and IP6, the FAC decreased only in 80:20 dilutions. On mixing NaOCl and AHA, the FAC increased on increasing dilution in all three proportions. Conclusion: The FAC on the combination of NaOCl with AHA, PAA, and IP6 remained unaltered or decreased marginally, suggesting that the antimicrobial properties of NaOCl might be preserved.https://journals.lww.com/10.4103/endo.endo_219_24etidronic acidfree available chlorineglycolic acidperacetic acidphytic acidsodium hypochlorite |
| spellingShingle | Somya Tyagi Sonali Taneja Kandasamy Nagarajan Divya Chowdhary Comparative evaluation of free available chlorine in sodium hypochlorite solutions admixed with novel chelating agents Endodontology etidronic acid free available chlorine glycolic acid peracetic acid phytic acid sodium hypochlorite |
| title | Comparative evaluation of free available chlorine in sodium hypochlorite solutions admixed with novel chelating agents |
| title_full | Comparative evaluation of free available chlorine in sodium hypochlorite solutions admixed with novel chelating agents |
| title_fullStr | Comparative evaluation of free available chlorine in sodium hypochlorite solutions admixed with novel chelating agents |
| title_full_unstemmed | Comparative evaluation of free available chlorine in sodium hypochlorite solutions admixed with novel chelating agents |
| title_short | Comparative evaluation of free available chlorine in sodium hypochlorite solutions admixed with novel chelating agents |
| title_sort | comparative evaluation of free available chlorine in sodium hypochlorite solutions admixed with novel chelating agents |
| topic | etidronic acid free available chlorine glycolic acid peracetic acid phytic acid sodium hypochlorite |
| url | https://journals.lww.com/10.4103/endo.endo_219_24 |
| work_keys_str_mv | AT somyatyagi comparativeevaluationoffreeavailablechlorineinsodiumhypochloritesolutionsadmixedwithnovelchelatingagents AT sonalitaneja comparativeevaluationoffreeavailablechlorineinsodiumhypochloritesolutionsadmixedwithnovelchelatingagents AT kandasamynagarajan comparativeevaluationoffreeavailablechlorineinsodiumhypochloritesolutionsadmixedwithnovelchelatingagents AT divyachowdhary comparativeevaluationoffreeavailablechlorineinsodiumhypochloritesolutionsadmixedwithnovelchelatingagents |