Post-Translational Modification of p62: Roles and Regulations in Autophagy

Post-Translational Modification of p62: Roles and Regulations in Autophagy

Autophagy is a highly conserved cellular process that plays a crucial role in maintaining cellular homeostasis by degrading damaged organelles, misfolded proteins, and other cellular components. p62/SQSTM1 functions as a selective autophagy receptor by binding polyubiquitinated cargo through its UBA...

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Bibliographic Details
Main Authors: Shuai Xiao, Yeping Yu, Meng Liao, Dandan Song, Xiaozhen Xu, Lingli Tian, Rui Zhang, Hao Lyu, Dong Guo, Qi Zhang, Xing-Zhen Chen, Cefan Zhou, Jingfeng Tang
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
post-translational modifications
autophagy
p62
oligomerization
Online Access:https://www.mdpi.com/2073-4409/14/13/1016
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