Multiple ionization patterns enable UHPLC-Q-Orbitrap MS/MS to quantify 80 compounds in Tongmai Granule and recommend new anti-counterfeiting Q-markers for Pharmacopoeia

Multiple ionization patterns enable UHPLC-Q-Orbitrap MS/MS to quantify 80 compounds in Tongmai Granule and recommend new anti-counterfeiting Q-markers for Pharmacopoeia

Abstract To explore the enabling role of multiple ionization patterns in UHPLC-Q-Orbitrap MS/MS analysis of complicated traditional Chinese herbal medicines, Tongmai Granule (TMG) composed of Salviae Miltiorrhizae Radix et Rhizoma (SM), Chuanxiong Rhizoma (CR), and Puerariae Lobatae Radix (PL), is i...

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Bibliographic Details
Main Authors: Rongxin Cai, Honghong Liang, Xican Li, Hanxiao Chai, Yongbai Liang, Yuhan Huang, Meilin He, Guihua Jiang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Journal of Saudi Chemical Society
Subjects:
Tongmai Granule
Simultaneous Quantification
Q-markers
UHPLC-Q-Orbitrap MS/MS
LC–MS
Multiple adducts
Online Access:https://doi.org/10.1007/s44442-025-00013-1
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