Plant-derived extracts and natural products with antiviral activity
In recent years, several viral epidemics and pandemics have emerged, leading to significant increases in both morbidity and mortality rates. This highlights the urgent need for the discovery of effective antiviral agents. A promising alternative approach to treating viral infections is the use of me...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Virology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fviro.2025.1632734/full |
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| author | Giovane de Jesus Gomes Ribeiro Edmarcia Elisa de Souza Giuseppe Palmisano Edison Luiz Durigon Edison Luiz Durigon Eva Liebau Carsten Wrenger Carsten Wrenger |
| author_facet | Giovane de Jesus Gomes Ribeiro Edmarcia Elisa de Souza Giuseppe Palmisano Edison Luiz Durigon Edison Luiz Durigon Eva Liebau Carsten Wrenger Carsten Wrenger |
| author_sort | Giovane de Jesus Gomes Ribeiro |
| collection | DOAJ |
| description | In recent years, several viral epidemics and pandemics have emerged, leading to significant increases in both morbidity and mortality rates. This highlights the urgent need for the discovery of effective antiviral agents. A promising alternative approach to treating viral infections is the use of medicinal plants and their secondary metabolites. Plant-derived natural products have long been a valuable source for discovering novel therapeutic agents, owing to their chemical and structural diversity. This mini-review focuses on the antiviral activity of various enriched extracts and phytoconstituents isolated from medicinal plants, which have demonstrated efficacy against viral infections caused by the influenza virus, coronaviruses, arboviruses such as dengue, chikungunya, Zika, and Mayaro, as well as the human immunodeficiency virus (HIV). |
| format | Article |
| id | doaj-art-ca2f72047c7344a68f2c3d4981da35dc |
| institution | DOAJ |
| issn | 2673-818X |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Virology |
| spelling | doaj-art-ca2f72047c7344a68f2c3d4981da35dc2025-08-20T02:57:30ZengFrontiers Media S.A.Frontiers in Virology2673-818X2025-08-01510.3389/fviro.2025.16327341632734Plant-derived extracts and natural products with antiviral activityGiovane de Jesus Gomes Ribeiro0Edmarcia Elisa de Souza1Giuseppe Palmisano2Edison Luiz Durigon3Edison Luiz Durigon4Eva Liebau5Carsten Wrenger6Carsten Wrenger7Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, BrazilDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, BrazilDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, BrazilDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, BrazilInstitut Pasteur de São Paulo, São Paulo, BrazilInstitute of Integrated Cell Biology and Physiology, University of Münster, Münster, GermanyDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, BrazilInstitut Pasteur de São Paulo, São Paulo, BrazilIn recent years, several viral epidemics and pandemics have emerged, leading to significant increases in both morbidity and mortality rates. This highlights the urgent need for the discovery of effective antiviral agents. A promising alternative approach to treating viral infections is the use of medicinal plants and their secondary metabolites. Plant-derived natural products have long been a valuable source for discovering novel therapeutic agents, owing to their chemical and structural diversity. This mini-review focuses on the antiviral activity of various enriched extracts and phytoconstituents isolated from medicinal plants, which have demonstrated efficacy against viral infections caused by the influenza virus, coronaviruses, arboviruses such as dengue, chikungunya, Zika, and Mayaro, as well as the human immunodeficiency virus (HIV).https://www.frontiersin.org/articles/10.3389/fviro.2025.1632734/fullmedicinal plantsantiviral and pharmacological targetsSARS-CoV-2ZIKVCHIKVMAYV |
| spellingShingle | Giovane de Jesus Gomes Ribeiro Edmarcia Elisa de Souza Giuseppe Palmisano Edison Luiz Durigon Edison Luiz Durigon Eva Liebau Carsten Wrenger Carsten Wrenger Plant-derived extracts and natural products with antiviral activity Frontiers in Virology medicinal plants antiviral and pharmacological targets SARS-CoV-2 ZIKV CHIKV MAYV |
| title | Plant-derived extracts and natural products with antiviral activity |
| title_full | Plant-derived extracts and natural products with antiviral activity |
| title_fullStr | Plant-derived extracts and natural products with antiviral activity |
| title_full_unstemmed | Plant-derived extracts and natural products with antiviral activity |
| title_short | Plant-derived extracts and natural products with antiviral activity |
| title_sort | plant derived extracts and natural products with antiviral activity |
| topic | medicinal plants antiviral and pharmacological targets SARS-CoV-2 ZIKV CHIKV MAYV |
| url | https://www.frontiersin.org/articles/10.3389/fviro.2025.1632734/full |
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