Polydiacetylene (PDA) Embedded Polymer-Based Network Structure for Biosensor Applications
Biosensors, which combine physical transducers with biorecognition elements, have seen significant advancement due to the heightened interest in rapid diagnostic technologies across a number of fields, including medical diagnostics, environmental monitoring, and food safety. In particular, polydiace...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-01-01
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| Series: | Gels |
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| Online Access: | https://www.mdpi.com/2310-2861/11/1/66 |
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| author | Huisoo Jang Junhyeon Jeon Mingyeong Shin Geonha Kang Hyunil Ryu Sun Min Kim Tae-Joon Jeon |
| author_facet | Huisoo Jang Junhyeon Jeon Mingyeong Shin Geonha Kang Hyunil Ryu Sun Min Kim Tae-Joon Jeon |
| author_sort | Huisoo Jang |
| collection | DOAJ |
| description | Biosensors, which combine physical transducers with biorecognition elements, have seen significant advancement due to the heightened interest in rapid diagnostic technologies across a number of fields, including medical diagnostics, environmental monitoring, and food safety. In particular, polydiacetylene (PDA) is gaining attention as an ideal material for label-free colorimetric biosensor development due to its unique color-changing properties in response to external stimuli. PDA forms through the self-assembly of diacetylene monomers, with color change occurring as its conjugated backbone twists in response to stimuli such as temperature, pH, and chemical interactions. This color change enables the detection of biomarkers, metal ions, and toxic compounds. Moreover, the combination of PDA with polymeric structures including hydrogels further enhances the sensitivity and structural stability of PDA-based biosensors, making them reliable and effective in complex biological and environmental conditions. This review comprehensively examines recent research trends and applications of PDA–polymeric structure hybrid biosensors, while discussing future directions and potential advancements in this field. |
| format | Article |
| id | doaj-art-ca1eb15c24474c2ca6c42bd3dce5a6ac |
| institution | Kabale University |
| issn | 2310-2861 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gels |
| spelling | doaj-art-ca1eb15c24474c2ca6c42bd3dce5a6ac2025-01-24T13:33:59ZengMDPI AGGels2310-28612025-01-011116610.3390/gels11010066Polydiacetylene (PDA) Embedded Polymer-Based Network Structure for Biosensor ApplicationsHuisoo Jang0Junhyeon Jeon1Mingyeong Shin2Geonha Kang3Hyunil Ryu4Sun Min Kim5Tae-Joon Jeon6Industrial Science and Technology Research Institute, Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of KoreaBiohybrid Systems Research Center (BSRC), Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of KoreaDepartment of Food and Nutrition, Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of KoreaDepartment of Mechanical Engineering, Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of KoreaBiohybrid Systems Research Center (BSRC), Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of KoreaBiohybrid Systems Research Center (BSRC), Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of KoreaBiohybrid Systems Research Center (BSRC), Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of KoreaBiosensors, which combine physical transducers with biorecognition elements, have seen significant advancement due to the heightened interest in rapid diagnostic technologies across a number of fields, including medical diagnostics, environmental monitoring, and food safety. In particular, polydiacetylene (PDA) is gaining attention as an ideal material for label-free colorimetric biosensor development due to its unique color-changing properties in response to external stimuli. PDA forms through the self-assembly of diacetylene monomers, with color change occurring as its conjugated backbone twists in response to stimuli such as temperature, pH, and chemical interactions. This color change enables the detection of biomarkers, metal ions, and toxic compounds. Moreover, the combination of PDA with polymeric structures including hydrogels further enhances the sensitivity and structural stability of PDA-based biosensors, making them reliable and effective in complex biological and environmental conditions. This review comprehensively examines recent research trends and applications of PDA–polymeric structure hybrid biosensors, while discussing future directions and potential advancements in this field.https://www.mdpi.com/2310-2861/11/1/66colorimetric biosensorspolydiacetylenehydrogelpolymeric structuresynthetic polymerspoint-of-care detection |
| spellingShingle | Huisoo Jang Junhyeon Jeon Mingyeong Shin Geonha Kang Hyunil Ryu Sun Min Kim Tae-Joon Jeon Polydiacetylene (PDA) Embedded Polymer-Based Network Structure for Biosensor Applications Gels colorimetric biosensors polydiacetylene hydrogel polymeric structure synthetic polymers point-of-care detection |
| title | Polydiacetylene (PDA) Embedded Polymer-Based Network Structure for Biosensor Applications |
| title_full | Polydiacetylene (PDA) Embedded Polymer-Based Network Structure for Biosensor Applications |
| title_fullStr | Polydiacetylene (PDA) Embedded Polymer-Based Network Structure for Biosensor Applications |
| title_full_unstemmed | Polydiacetylene (PDA) Embedded Polymer-Based Network Structure for Biosensor Applications |
| title_short | Polydiacetylene (PDA) Embedded Polymer-Based Network Structure for Biosensor Applications |
| title_sort | polydiacetylene pda embedded polymer based network structure for biosensor applications |
| topic | colorimetric biosensors polydiacetylene hydrogel polymeric structure synthetic polymers point-of-care detection |
| url | https://www.mdpi.com/2310-2861/11/1/66 |
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