A Rare Case of Hypophysitis Due to Tuberculosis with an Atypical Presentation of Normal Pituitary Markers
Hypophysitis developing secondary to tuberculosis is a very rare clinical entity. Hypophysitis occurs because of inflammation and it may affect the anterior, infundibulum, posterior, or entire pituitary gland. Here, we are presenting a case of a young male having tubercular meningitis who was taking...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer – Medknow Publications
2024-01-01
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| Series: | Journal of Integrated Health Sciences |
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| Online Access: | https://journals.lww.com/10.4103/jihs.jihs_8_24 |
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| author | Jinal Shah Shubham Darda Prasen Shah Jitendra D. Lakhani |
| author_facet | Jinal Shah Shubham Darda Prasen Shah Jitendra D. Lakhani |
| author_sort | Jinal Shah |
| collection | DOAJ |
| description | Hypophysitis developing secondary to tuberculosis is a very rare clinical entity. Hypophysitis occurs because of inflammation and it may affect the anterior, infundibulum, posterior, or entire pituitary gland. Here, we are presenting a case of a young male having tubercular meningitis who was taking antitubercular treatment for the last 2 months and was having disseminated tuberculosis. The patient presented with severe headache with fever and 4–5 episodes of vomiting. The patient presented with the affection of consciousness in the form of confusion, irritability, and disorientation. High-resolution CT thorax was suggestive of pulmonary tuberculosis (Koch’s) with centrilobular nodules and a tree-in-bud appearance. Magnetic resonance imaging brain showed prominent leptomeningeal enhancement with an enlarged pituitary gland with enlarged enhancing stalk suggestive of hypophysitis. The hypophysitis case developing secondary to tuberculosis as a very rare entity is discussed in this case report. This case is also an atypical presentation wherein the pituitary markers are normal in hypophysitis. |
| format | Article |
| id | doaj-art-ca1a7e2bc0e74d37bbfe5794edbf87fa |
| institution | Kabale University |
| issn | 2347-6486 2347-6494 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer – Medknow Publications |
| record_format | Article |
| series | Journal of Integrated Health Sciences |
| spelling | doaj-art-ca1a7e2bc0e74d37bbfe5794edbf87fa2025-08-20T03:42:35ZengWolters Kluwer – Medknow PublicationsJournal of Integrated Health Sciences2347-64862347-64942024-01-01121767910.4103/jihs.jihs_8_24A Rare Case of Hypophysitis Due to Tuberculosis with an Atypical Presentation of Normal Pituitary MarkersJinal ShahShubham DardaPrasen ShahJitendra D. LakhaniHypophysitis developing secondary to tuberculosis is a very rare clinical entity. Hypophysitis occurs because of inflammation and it may affect the anterior, infundibulum, posterior, or entire pituitary gland. Here, we are presenting a case of a young male having tubercular meningitis who was taking antitubercular treatment for the last 2 months and was having disseminated tuberculosis. The patient presented with severe headache with fever and 4–5 episodes of vomiting. The patient presented with the affection of consciousness in the form of confusion, irritability, and disorientation. High-resolution CT thorax was suggestive of pulmonary tuberculosis (Koch’s) with centrilobular nodules and a tree-in-bud appearance. Magnetic resonance imaging brain showed prominent leptomeningeal enhancement with an enlarged pituitary gland with enlarged enhancing stalk suggestive of hypophysitis. The hypophysitis case developing secondary to tuberculosis as a very rare entity is discussed in this case report. This case is also an atypical presentation wherein the pituitary markers are normal in hypophysitis.https://journals.lww.com/10.4103/jihs.jihs_8_24hypophysitismeningitistuberculosis |
| spellingShingle | Jinal Shah Shubham Darda Prasen Shah Jitendra D. Lakhani A Rare Case of Hypophysitis Due to Tuberculosis with an Atypical Presentation of Normal Pituitary Markers Journal of Integrated Health Sciences hypophysitis meningitis tuberculosis |
| title | A Rare Case of Hypophysitis Due to Tuberculosis with an Atypical Presentation of Normal Pituitary Markers |
| title_full | A Rare Case of Hypophysitis Due to Tuberculosis with an Atypical Presentation of Normal Pituitary Markers |
| title_fullStr | A Rare Case of Hypophysitis Due to Tuberculosis with an Atypical Presentation of Normal Pituitary Markers |
| title_full_unstemmed | A Rare Case of Hypophysitis Due to Tuberculosis with an Atypical Presentation of Normal Pituitary Markers |
| title_short | A Rare Case of Hypophysitis Due to Tuberculosis with an Atypical Presentation of Normal Pituitary Markers |
| title_sort | rare case of hypophysitis due to tuberculosis with an atypical presentation of normal pituitary markers |
| topic | hypophysitis meningitis tuberculosis |
| url | https://journals.lww.com/10.4103/jihs.jihs_8_24 |
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