Biological functions of extracellular vesicle double C2-like domain beta in cervical cancer

Biological functions of extracellular vesicle double C2-like domain beta in cervical cancer

Abstract Double C-2 Like Domain Beta (DOC2B) located at 17q13.3 prevents metastasis by senescence induction and epithelial to mesenchymal transition inhibition in cervical cancer (CC). The extracellular vesicle (EV) mediated trafficking of DOC2B and its impact on tumor suppressive activity are not i...

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Bibliographic Details
Main Authors: Sangavi Eswaran, Samatha Bhat, Dinesh Upadhya, Roshan Mascarenhas, Shama Prasada Kabekkodu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Cervical cancer
DOC2B
Extracellular vesicles
Calcium
EMT
Senescence
Online Access:https://doi.org/10.1038/s41598-024-84643-2
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