Foundations of a knee joint digital twin from qMRI biomarkers for osteoarthritis and knee replacement

Abstract This study forms the basis of a digital twin system of the knee joint, using advanced quantitative MRI (qMRI) and machine learning to advance precision health in osteoarthritis (OA) management and knee replacement (KR) prediction. We combined deep learning-based segmentation of knee joint s...

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Bibliographic Details
Main Authors: Gabrielle Hoyer, Kenneth T. Gao, Felix G. Gassert, Johanna Luitjens, Fei Jiang, Sharmila Majumdar, Valentina Pedoia
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-025-01507-3
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