Evaluation of pain intensity and airway changes in non-growing patients treated by MARPE with and without micro-osteoperforation: a randomized clinical trial

Abstract Trial design Parallel. Objectives To assess the effect of mini-screw assisted rapid palatal expansion (MARPE) with/without micro-osteoperforation (MOP) on the airway and pain intensity in non-growing patients with maxillary transverse deficiency. Method Two equal groups of twenty-four indiv...

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Main Authors: Moataz Elshehaby, Nehal Fouad Albelasy, Mohamed A. Elbialy, Ahmad Mohammed Hafez, Yasser Lotfy Abdelnaby
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Oral Health
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Online Access:https://doi.org/10.1186/s12903-024-05196-4
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author Moataz Elshehaby
Nehal Fouad Albelasy
Mohamed A. Elbialy
Ahmad Mohammed Hafez
Yasser Lotfy Abdelnaby
author_facet Moataz Elshehaby
Nehal Fouad Albelasy
Mohamed A. Elbialy
Ahmad Mohammed Hafez
Yasser Lotfy Abdelnaby
author_sort Moataz Elshehaby
collection DOAJ
description Abstract Trial design Parallel. Objectives To assess the effect of mini-screw assisted rapid palatal expansion (MARPE) with/without micro-osteoperforation (MOP) on the airway and pain intensity in non-growing patients with maxillary transverse deficiency. Method Two equal groups of twenty-four individuals aged ≥ 19 years old with maxillary transverse deficit were randomly assigned. MOP-facilitated MARPE was used to treat one group (MMG), and the other group was treated with MARPE without MOP (NMG). For airway evaluation, CBCT images were obtained 2 months before starting the palatal expansion and 3 months after finishing the expansion in 28 days. The Visual Analogue Scale (VAS) was used to measure the pain level. Results Significant suture opening was observed in both groups. All linear measurements of the nasal cavity and volumetric measurements of the nasal passage and oropharyngeal airway increased significantly in both groups, with no significant difference between them. Moderate pain was experienced in the first two weeks of expansion in MMG (5.11 ± 0.30), while more significant pain was recorded in NMG (6.87 ± 0.40). Pain decreased significantly in the following two weeks in MMG (2.77 ± 0.39) and in NMG (5.11 ± 0.32), with a significant difference between the two groups throughout the entire duration of expansion. Conclusion Transverse maxillary deficit was successfully treated with both expansion methods, with and without MOP, with comparable skeletal effects at the nasal levels and airway volumetric improvement. So, MOP did not provide any further advantage in improving the airway volume after maxillary expansion. However, it significantly reduced pain intensity throughout the entire duration of expansion. Trial registration The protocol registration and results system (PRS) of ClinicalTrials.gov has this RCT registered under the number NCT06502041 on 13/07/2024.
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spelling doaj-art-ca15e41f47b5452e8bd6fb98b5720bba2025-08-20T02:22:25ZengBMCBMC Oral Health1472-68312024-11-0124111210.1186/s12903-024-05196-4Evaluation of pain intensity and airway changes in non-growing patients treated by MARPE with and without micro-osteoperforation: a randomized clinical trialMoataz Elshehaby0Nehal Fouad Albelasy1Mohamed A. Elbialy2Ahmad Mohammed Hafez3Yasser Lotfy Abdelnaby4Department of Orthodontics, Faculty of Oral and Dental Medicine Dentistry, Delta University for Science and TechnologyDepartment of Orthodontics, Faculty of Dentistry, Mansoura UniversityDepartment of Orthodontics, Faculty of Dentistry, Mansoura UniversityDepartment of Orthodontics, Faculty of Dentistry, Mansoura UniversityDepartment of Orthodontics, Faculty of Dentistry, Mansoura UniversityAbstract Trial design Parallel. Objectives To assess the effect of mini-screw assisted rapid palatal expansion (MARPE) with/without micro-osteoperforation (MOP) on the airway and pain intensity in non-growing patients with maxillary transverse deficiency. Method Two equal groups of twenty-four individuals aged ≥ 19 years old with maxillary transverse deficit were randomly assigned. MOP-facilitated MARPE was used to treat one group (MMG), and the other group was treated with MARPE without MOP (NMG). For airway evaluation, CBCT images were obtained 2 months before starting the palatal expansion and 3 months after finishing the expansion in 28 days. The Visual Analogue Scale (VAS) was used to measure the pain level. Results Significant suture opening was observed in both groups. All linear measurements of the nasal cavity and volumetric measurements of the nasal passage and oropharyngeal airway increased significantly in both groups, with no significant difference between them. Moderate pain was experienced in the first two weeks of expansion in MMG (5.11 ± 0.30), while more significant pain was recorded in NMG (6.87 ± 0.40). Pain decreased significantly in the following two weeks in MMG (2.77 ± 0.39) and in NMG (5.11 ± 0.32), with a significant difference between the two groups throughout the entire duration of expansion. Conclusion Transverse maxillary deficit was successfully treated with both expansion methods, with and without MOP, with comparable skeletal effects at the nasal levels and airway volumetric improvement. So, MOP did not provide any further advantage in improving the airway volume after maxillary expansion. However, it significantly reduced pain intensity throughout the entire duration of expansion. Trial registration The protocol registration and results system (PRS) of ClinicalTrials.gov has this RCT registered under the number NCT06502041 on 13/07/2024.https://doi.org/10.1186/s12903-024-05196-4MARPEMicro-osteoperforationMaxillary transverse deficiencyPainAirway volumeRandomized clinical trial
spellingShingle Moataz Elshehaby
Nehal Fouad Albelasy
Mohamed A. Elbialy
Ahmad Mohammed Hafez
Yasser Lotfy Abdelnaby
Evaluation of pain intensity and airway changes in non-growing patients treated by MARPE with and without micro-osteoperforation: a randomized clinical trial
BMC Oral Health
MARPE
Micro-osteoperforation
Maxillary transverse deficiency
Pain
Airway volume
Randomized clinical trial
title Evaluation of pain intensity and airway changes in non-growing patients treated by MARPE with and without micro-osteoperforation: a randomized clinical trial
title_full Evaluation of pain intensity and airway changes in non-growing patients treated by MARPE with and without micro-osteoperforation: a randomized clinical trial
title_fullStr Evaluation of pain intensity and airway changes in non-growing patients treated by MARPE with and without micro-osteoperforation: a randomized clinical trial
title_full_unstemmed Evaluation of pain intensity and airway changes in non-growing patients treated by MARPE with and without micro-osteoperforation: a randomized clinical trial
title_short Evaluation of pain intensity and airway changes in non-growing patients treated by MARPE with and without micro-osteoperforation: a randomized clinical trial
title_sort evaluation of pain intensity and airway changes in non growing patients treated by marpe with and without micro osteoperforation a randomized clinical trial
topic MARPE
Micro-osteoperforation
Maxillary transverse deficiency
Pain
Airway volume
Randomized clinical trial
url https://doi.org/10.1186/s12903-024-05196-4
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