Sirtuins and mechanisms of diabetic lung damage: a scientific discussion. A review
Induced tissue damage in target organs (kidneys, heart, eyes, liver, skin, nervous system) significantly contributes to the morbidity and mortality of patients from diabetes mellitus (DM). In recent decades, the question has been actively discussed: should the lungs be regarded as a target organ for...
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| Format: | Article |
| Language: | Russian |
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ZAO "Consilium Medicum"
2024-10-01
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| Series: | Consilium Medicum |
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| Online Access: | https://consilium.orscience.ru/2075-1753/article/viewFile/636961/152390 |
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| author | Sergei L. Babak Marina V. Gorbunova Andrey G. Malyavin Vladislav S. Borovitsky |
| author_facet | Sergei L. Babak Marina V. Gorbunova Andrey G. Malyavin Vladislav S. Borovitsky |
| author_sort | Sergei L. Babak |
| collection | DOAJ |
| description | Induced tissue damage in target organs (kidneys, heart, eyes, liver, skin, nervous system) significantly contributes to the morbidity and mortality of patients from diabetes mellitus (DM). In recent decades, the question has been actively discussed: should the lungs be regarded as a target organ for diabetes? The c collected data demonstrate histological and functional lung disorders in DM patients. This suggests that the lungs are a target organ for diabetes. It is known that sirtuins regulate a number of physiological processes and affect obesity, insulin resistance, type 2 DM, heart disease and aging. In this review, we have tried to summarize the knowledge about the contribution of sirtuins to cellular regulation and the formation of pulmonary disease in patients with type 2 DM. |
| format | Article |
| id | doaj-art-ca11c55df8244fe0ae8fc82887ddbb56 |
| institution | Kabale University |
| issn | 2075-1753 2542-2170 |
| language | Russian |
| publishDate | 2024-10-01 |
| publisher | ZAO "Consilium Medicum" |
| record_format | Article |
| series | Consilium Medicum |
| spelling | doaj-art-ca11c55df8244fe0ae8fc82887ddbb562025-01-15T11:58:17ZrusZAO "Consilium Medicum"Consilium Medicum2075-17532542-21702024-10-0126962462710.26442/20751753.2024.9.2029734872Sirtuins and mechanisms of diabetic lung damage: a scientific discussion. A reviewSergei L. Babak0https://orcid.org/0000-0002-6571-1220Marina V. Gorbunova1https://orcid.org/0000-0002-2039-0072Andrey G. Malyavin2https://orcid.org/0000-0002-6128-5914Vladislav S. Borovitsky3https://orcid.org/0009-0007-5964-7051Russian University of MedicineRussian University of MedicineRussian University of MedicineResearch Institute of the Federal Penitentiary Service of RussiaInduced tissue damage in target organs (kidneys, heart, eyes, liver, skin, nervous system) significantly contributes to the morbidity and mortality of patients from diabetes mellitus (DM). In recent decades, the question has been actively discussed: should the lungs be regarded as a target organ for diabetes? The c collected data demonstrate histological and functional lung disorders in DM patients. This suggests that the lungs are a target organ for diabetes. It is known that sirtuins regulate a number of physiological processes and affect obesity, insulin resistance, type 2 DM, heart disease and aging. In this review, we have tried to summarize the knowledge about the contribution of sirtuins to cellular regulation and the formation of pulmonary disease in patients with type 2 DM.https://consilium.orscience.ru/2075-1753/article/viewFile/636961/152390diabetes mellitusdiabetic lungsirtuins |
| spellingShingle | Sergei L. Babak Marina V. Gorbunova Andrey G. Malyavin Vladislav S. Borovitsky Sirtuins and mechanisms of diabetic lung damage: a scientific discussion. A review Consilium Medicum diabetes mellitus diabetic lung sirtuins |
| title | Sirtuins and mechanisms of diabetic lung damage: a scientific discussion. A review |
| title_full | Sirtuins and mechanisms of diabetic lung damage: a scientific discussion. A review |
| title_fullStr | Sirtuins and mechanisms of diabetic lung damage: a scientific discussion. A review |
| title_full_unstemmed | Sirtuins and mechanisms of diabetic lung damage: a scientific discussion. A review |
| title_short | Sirtuins and mechanisms of diabetic lung damage: a scientific discussion. A review |
| title_sort | sirtuins and mechanisms of diabetic lung damage a scientific discussion a review |
| topic | diabetes mellitus diabetic lung sirtuins |
| url | https://consilium.orscience.ru/2075-1753/article/viewFile/636961/152390 |
| work_keys_str_mv | AT sergeilbabak sirtuinsandmechanismsofdiabeticlungdamageascientificdiscussionareview AT marinavgorbunova sirtuinsandmechanismsofdiabeticlungdamageascientificdiscussionareview AT andreygmalyavin sirtuinsandmechanismsofdiabeticlungdamageascientificdiscussionareview AT vladislavsborovitsky sirtuinsandmechanismsofdiabeticlungdamageascientificdiscussionareview |