Latanoprost in the treatment of primary open-angle glaucoma

Latanoprost, an analogue of class F2α prostaglandins, has been on the glaucoma hypotensive treatment market for almost 30 years, being the drug of first choice due to its high efficiency, good tolerability and minimal dosage. The drug is effective in all ages and is approved in pediatric practice fr...

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Main Authors: S. Yu. Petrov, O. I. Markelova
Format: Article
Language:Russian
Published: Real Time Ltd 2024-12-01
Series:Российский офтальмологический журнал
Subjects:
Online Access:https://roj.igb.ru/jour/article/view/1637
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author S. Yu. Petrov
O. I. Markelova
author_facet S. Yu. Petrov
O. I. Markelova
author_sort S. Yu. Petrov
collection DOAJ
description Latanoprost, an analogue of class F2α prostaglandins, has been on the glaucoma hypotensive treatment market for almost 30 years, being the drug of first choice due to its high efficiency, good tolerability and minimal dosage. The drug is effective in all ages and is approved in pediatric practice from 1 year. According to numerous studies, latanoprost monotherapy can reduce IOP by an average of 22–39 % from the initial level over several years; a decrease in the hypotensive effect over time has not been noted. Latanoprost is compatible with all other groups of antiglaucoma drugs, demonstrating an additive effect.
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institution Kabale University
issn 2072-0076
2587-5760
language Russian
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publisher Real Time Ltd
record_format Article
series Российский офтальмологический журнал
spelling doaj-art-ca0f8f582cb54554980e1f7e0963d0102025-08-20T03:40:10ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602024-12-0117414114710.21516/2072-0076-2024-17-4-141-147751Latanoprost in the treatment of primary open-angle glaucomaS. Yu. Petrov0O. I. Markelova1Helmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesLatanoprost, an analogue of class F2α prostaglandins, has been on the glaucoma hypotensive treatment market for almost 30 years, being the drug of first choice due to its high efficiency, good tolerability and minimal dosage. The drug is effective in all ages and is approved in pediatric practice from 1 year. According to numerous studies, latanoprost monotherapy can reduce IOP by an average of 22–39 % from the initial level over several years; a decrease in the hypotensive effect over time has not been noted. Latanoprost is compatible with all other groups of antiglaucoma drugs, demonstrating an additive effect.https://roj.igb.ru/jour/article/view/1637glaucomalatanoprosthypotensive treatmentmonotherapy
spellingShingle S. Yu. Petrov
O. I. Markelova
Latanoprost in the treatment of primary open-angle glaucoma
Российский офтальмологический журнал
glaucoma
latanoprost
hypotensive treatment
monotherapy
title Latanoprost in the treatment of primary open-angle glaucoma
title_full Latanoprost in the treatment of primary open-angle glaucoma
title_fullStr Latanoprost in the treatment of primary open-angle glaucoma
title_full_unstemmed Latanoprost in the treatment of primary open-angle glaucoma
title_short Latanoprost in the treatment of primary open-angle glaucoma
title_sort latanoprost in the treatment of primary open angle glaucoma
topic glaucoma
latanoprost
hypotensive treatment
monotherapy
url https://roj.igb.ru/jour/article/view/1637
work_keys_str_mv AT syupetrov latanoprostinthetreatmentofprimaryopenangleglaucoma
AT oimarkelova latanoprostinthetreatmentofprimaryopenangleglaucoma