Cadmium induced ferroptosis and inflammation in sheep via targeting ACSL4/NF-κB axis

Cadmium induced ferroptosis and inflammation in sheep via targeting ACSL4/NF-κB axis

IntroductionCadmium, a major environmental contaminant, induces progressive intestinal damage through bioaccumulation in vivo. Elucidating its pathogenic mechanisms is crucial for developing therapeutic interventions.MethodsThis study employed multi-omics approaches to systematically investigated ca...

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Bibliographic Details
Main Authors: Zimeng Ma, Shuo Yan, Huimin Zhang, Ruilin Du, Xinyue Cheng, Siqin Bao, Xihe Li, Yongli Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Veterinary Science
Subjects:
sheep
cadmium
intestine inflammation
mitochondrion
ferroptosis
NF-κB signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1617190/full
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