Combination of acne treatment in women with prevention of complications using standard schemes of systemic retinoids

Currently, the first-line drugs for acne treatment are systemic retinoids. This group of drugs has a pronounced hepatotoxic effect, which should be taken into account when using them in standard acne treatment schemes. The aim of the study was to study the effect of ursodeoxycholic acid on the toler...

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Main Authors: S. S. Ledentsova, N. I. Gulyaev, A. V. Gordienko, N. P. Gavrilova, L. S. Oreshko, P. V. Seliverstov
Format: Article
Language:Russian
Published: Open Systems Publication 2021-06-01
Series:Лечащий Врач
Subjects:
Online Access:https://journal.lvrach.ru/jour/article/view/145
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author S. S. Ledentsova
N. I. Gulyaev
A. V. Gordienko
N. P. Gavrilova
L. S. Oreshko
P. V. Seliverstov
author_facet S. S. Ledentsova
N. I. Gulyaev
A. V. Gordienko
N. P. Gavrilova
L. S. Oreshko
P. V. Seliverstov
author_sort S. S. Ledentsova
collection DOAJ
description Currently, the first-line drugs for acne treatment are systemic retinoids. This group of drugs has a pronounced hepatotoxic effect, which should be taken into account when using them in standard acne treatment schemes. The aim of the study was to study the effect of ursodeoxycholic acid on the tolerability and effectiveness of systemic isotretinoin therapy in patients with severe acne taking combined oral contraceptives.
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institution DOAJ
issn 1560-5175
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language Russian
publishDate 2021-06-01
publisher Open Systems Publication
record_format Article
series Лечащий Врач
spelling doaj-art-ca02af921ea9466fa3ff558d3190a5402025-08-20T02:49:05ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812021-06-0106858810.26295/OS.2020.30.33.015144Combination of acne treatment in women with prevention of complications using standard schemes of systemic retinoidsS. S. Ledentsova0N. I. Gulyaev1A. V. Gordienko2N. P. Gavrilova3L. S. Oreshko4P. V. Seliverstov5СПб ГБУЗ ГП №76ФГБВОУ ВМА им. С. М. КироваФГБВОУ ВМА им. С. М. КироваООО «Медицинский центр «МСЧ №24»ФГБОУ ВО СЗГМУ им. И. И. Мечникова Минздрава РоссииООО «Медицинский центр «МСЧ №24»Currently, the first-line drugs for acne treatment are systemic retinoids. This group of drugs has a pronounced hepatotoxic effect, which should be taken into account when using them in standard acne treatment schemes. The aim of the study was to study the effect of ursodeoxycholic acid on the tolerability and effectiveness of systemic isotretinoin therapy in patients with severe acne taking combined oral contraceptives.https://journal.lvrach.ru/jour/article/view/145acneside effects of therapyisotretinoinretinoidscocdrug liver damageursodeoxycholic acidprevention
spellingShingle S. S. Ledentsova
N. I. Gulyaev
A. V. Gordienko
N. P. Gavrilova
L. S. Oreshko
P. V. Seliverstov
Combination of acne treatment in women with prevention of complications using standard schemes of systemic retinoids
Лечащий Врач
acne
side effects of therapy
isotretinoin
retinoids
coc
drug liver damage
ursodeoxycholic acid
prevention
title Combination of acne treatment in women with prevention of complications using standard schemes of systemic retinoids
title_full Combination of acne treatment in women with prevention of complications using standard schemes of systemic retinoids
title_fullStr Combination of acne treatment in women with prevention of complications using standard schemes of systemic retinoids
title_full_unstemmed Combination of acne treatment in women with prevention of complications using standard schemes of systemic retinoids
title_short Combination of acne treatment in women with prevention of complications using standard schemes of systemic retinoids
title_sort combination of acne treatment in women with prevention of complications using standard schemes of systemic retinoids
topic acne
side effects of therapy
isotretinoin
retinoids
coc
drug liver damage
ursodeoxycholic acid
prevention
url https://journal.lvrach.ru/jour/article/view/145
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AT nigulyaev combinationofacnetreatmentinwomenwithpreventionofcomplicationsusingstandardschemesofsystemicretinoids
AT avgordienko combinationofacnetreatmentinwomenwithpreventionofcomplicationsusingstandardschemesofsystemicretinoids
AT npgavrilova combinationofacnetreatmentinwomenwithpreventionofcomplicationsusingstandardschemesofsystemicretinoids
AT lsoreshko combinationofacnetreatmentinwomenwithpreventionofcomplicationsusingstandardschemesofsystemicretinoids
AT pvseliverstov combinationofacnetreatmentinwomenwithpreventionofcomplicationsusingstandardschemesofsystemicretinoids