A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles.

A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles.

Previously we have shown that compacted DNA nanoparticles can drive high levels of transgene expression after subretinal injection in the mouse eye. Here we delivered compacted DNA nanoparticles containing a therapeutic gene to the retinas of a mouse model of retinitis pigmentosa. Nanoparticles cont...

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Bibliographic Details
Main Authors: Xue Cai, Zack Nash, Shannon M Conley, Steven J Fliesler, Mark J Cooper, Muna I Naash
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0005290&type=printable
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