Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans

Baccharis dracunculifolia DC (Asteraceae), popularly known as “alecrim-do-campo,” is largely distributed in South America, is shown to exhibit protective actions against gastric ulcers, has anti-inflammatory properties, and is hepatoprotective. Several essential oils obtained from Baccharis species...

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Main Authors: Vinícius Pedrazzi, Mateus Freire Leite, Reisla Cristina Tavares, Sandra Sato, Glauce Crivelaro do Nascimento, João Paulo Mardegan Issa
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2015/712683
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author Vinícius Pedrazzi
Mateus Freire Leite
Reisla Cristina Tavares
Sandra Sato
Glauce Crivelaro do Nascimento
João Paulo Mardegan Issa
author_facet Vinícius Pedrazzi
Mateus Freire Leite
Reisla Cristina Tavares
Sandra Sato
Glauce Crivelaro do Nascimento
João Paulo Mardegan Issa
author_sort Vinícius Pedrazzi
collection DOAJ
description Baccharis dracunculifolia DC (Asteraceae), popularly known as “alecrim-do-campo,” is largely distributed in South America, is shown to exhibit protective actions against gastric ulcers, has anti-inflammatory properties, and is hepatoprotective. Several essential oils obtained from Baccharis species possess biological activities, such as antimicrobial and antivirus activities. This randomized controlled trial evaluated the efficacy of B. dracunculifolia in the reduction of dental biofilm, comparing this natural product with other mouthwashes already known in the dental market. In measuring the time after use of mouthwash (t=1), there was no difference between products (P=0.602); that is, subjects in the study had a similar PI after the first use. After one week (t=2), there was no difference between the four products evaluated (P=0.674), so, all research individuals completed the study with a similar reduction in dental biofilm between themselves but it was different from initial state (Friedman test). It is possible to conclude that B. dracunculifolia had the same efficiency of the materials used to oral hygiene in reduction of dental plaque and, consequently, prevention of dental caries. Thus, we can consider B. dracunculifolia as a good candidate for new material to be implemented in dental care.
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institution Kabale University
issn 2356-6140
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language English
publishDate 2015-01-01
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series The Scientific World Journal
spelling doaj-art-c9fa3457ec0f48c385b37363728277352025-02-03T07:25:03ZengWileyThe Scientific World Journal2356-61401537-744X2015-01-01201510.1155/2015/712683712683Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in HumansVinícius Pedrazzi0Mateus Freire Leite1Reisla Cristina Tavares2Sandra Sato3Glauce Crivelaro do Nascimento4João Paulo Mardegan Issa5Department of Dental Materials and Prosthodontics, Ribeirão Preto Dentistry Faculty, University of São Paulo, 14040-904 Ribeirão Preto, SP, BrazilMultidisciplinary Institute for Health, Federal University of Bahia, Anísio Teixeira Campus, 45029-094 Vitoria da Conquista, BA, BrazilDepartment of Dental Materials and Prosthodontics, Ribeirão Preto Dentistry Faculty, University of São Paulo, 14040-904 Ribeirão Preto, SP, BrazilDepartment of Dental Materials and Prosthodontics, Ribeirão Preto Dentistry Faculty, University of São Paulo, 14040-904 Ribeirão Preto, SP, BrazilDepartment of Morphology, Physiology and Basic Pathology, Ribeirão Preto Dentistry Faculty, University of São Paulo, 14040-904 Ribeirão Preto, SP, BrazilDepartment of Morphology, Physiology and Basic Pathology, Ribeirão Preto Dentistry Faculty, University of São Paulo, 14040-904 Ribeirão Preto, SP, BrazilBaccharis dracunculifolia DC (Asteraceae), popularly known as “alecrim-do-campo,” is largely distributed in South America, is shown to exhibit protective actions against gastric ulcers, has anti-inflammatory properties, and is hepatoprotective. Several essential oils obtained from Baccharis species possess biological activities, such as antimicrobial and antivirus activities. This randomized controlled trial evaluated the efficacy of B. dracunculifolia in the reduction of dental biofilm, comparing this natural product with other mouthwashes already known in the dental market. In measuring the time after use of mouthwash (t=1), there was no difference between products (P=0.602); that is, subjects in the study had a similar PI after the first use. After one week (t=2), there was no difference between the four products evaluated (P=0.674), so, all research individuals completed the study with a similar reduction in dental biofilm between themselves but it was different from initial state (Friedman test). It is possible to conclude that B. dracunculifolia had the same efficiency of the materials used to oral hygiene in reduction of dental plaque and, consequently, prevention of dental caries. Thus, we can consider B. dracunculifolia as a good candidate for new material to be implemented in dental care.http://dx.doi.org/10.1155/2015/712683
spellingShingle Vinícius Pedrazzi
Mateus Freire Leite
Reisla Cristina Tavares
Sandra Sato
Glauce Crivelaro do Nascimento
João Paulo Mardegan Issa
Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans
The Scientific World Journal
title Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans
title_full Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans
title_fullStr Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans
title_full_unstemmed Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans
title_short Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans
title_sort herbal mouthwash containing extracts of baccharis dracunculifolia as agent for the control of biofilm clinical evaluation in humans
url http://dx.doi.org/10.1155/2015/712683
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