Differential effects of GLP-1 receptor agonists on diabetic osteopathy in type 2 diabetes: a patient-stratified network meta-analysis

Differential effects of GLP-1 receptor agonists on diabetic osteopathy in type 2 diabetes: a patient-stratified network meta-analysis

Abstract Introduction Diabetic osteopathy is a skeletal disorder that is characterized by increased fracture risk despite normal bone mineral density. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as important therapeutic agents for type 2 diabetes mellitus (T2DM), but their eff...

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Main Authors: Yazan Jumah Alalwani, Ali Saad Alshahrani, Aseel Ibrahem Alsudays, Reema Nasser Awad Almutairi, Rana Ali Hassan Arab, Reema Safar Ali Alqahtani, Omar Saad Alrefaei, Rana Alqahtani, Meshal Salman Bin Ofaysan, Ahmed Y. Azzam, Ammar K. Alomran
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Musculoskeletal Disorders
Subjects:
Type 2 diabetes mellitus
Diabetic osteopathy
GLP-1 receptor agonists
Skeletal disorders
Bone health
Online Access:https://doi.org/10.1186/s12891-025-09022-y
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