Linear classification of healthy people and patients with valvular heart diseases based on heart rate variability indices derived from electrocardiograms

Heart rate variability (HRV) is an important marker in various cardiovascular and non-cardiovascular conditions. This study aimed to evaluate the effectiveness of three linear models (Logistic Regression, Ridge Regression, Support Vector Machine) in distinguishing between healthy individuals and tho...

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Main Authors: Siecinski Szymon, Doniec Rafal Jan, Grzegorzek Marcin
Format: Article
Language:English
Published: De Gruyter 2024-12-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2024-2144
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author Siecinski Szymon
Doniec Rafal Jan
Grzegorzek Marcin
author_facet Siecinski Szymon
Doniec Rafal Jan
Grzegorzek Marcin
author_sort Siecinski Szymon
collection DOAJ
description Heart rate variability (HRV) is an important marker in various cardiovascular and non-cardiovascular conditions. This study aimed to evaluate the effectiveness of three linear models (Logistic Regression, Ridge Regression, Support Vector Machine) in distinguishing between healthy individuals and those with valvular heart diseases (VHD) using time domain and frequency domain HRV indices derived from electrocardiographic (ECG) signals. We analyzed 59 recordings taken from two public datasets containing electrocardiographic, seismocardiographic, and gyrocardiographic signals from “Mechanocardiograms with ECG reference” and “An Open-access Database for the Evaluation of Cardio-mechanical Signals from Patients with Valvular Heart Diseases” that contain 29 and 30 recordings, respectively. HRV analysis included time and frequency domain indices and the linear models were evaluated using 5-fold stratified cross-validation. The highest sensitivity, PPV, accuracy and F1 score were observed for Logistic Regression (0.8810, 0.8819, 0.8814, 0.8812), followed by Ridge Regression (0.8805, 0.8858, 0.8814, 0.8808), and the lowest were observed for linear SVM (0.8310, 0.8318, 0.8305, 0.8305). The results showed that it is possible to distinguish healthy volunteers and patients with linear classifiers and time domain and frequency domain HRV indices obtained from ECG signals with decent performance.
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spelling doaj-art-c9e5dfdcf1af4bf59379ff72155c0b1d2025-08-20T02:58:46ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042024-12-0110458759010.1515/cdbme-2024-2144Linear classification of healthy people and patients with valvular heart diseases based on heart rate variability indices derived from electrocardiogramsSiecinski Szymon0Doniec Rafal Jan1Grzegorzek Marcin2Institute of Medical Informatics, University of Lubeck, Ratzeburger Allee 160,Lubeck, GermanyInstitute of Medical Informatics, University of Lubeck, Ratzeburger Allee 160,Lubeck, GermanyInstitute of Medical Informatics, University of Lubeck, Ratzeburger Allee 160,Lubeck, GermanyHeart rate variability (HRV) is an important marker in various cardiovascular and non-cardiovascular conditions. This study aimed to evaluate the effectiveness of three linear models (Logistic Regression, Ridge Regression, Support Vector Machine) in distinguishing between healthy individuals and those with valvular heart diseases (VHD) using time domain and frequency domain HRV indices derived from electrocardiographic (ECG) signals. We analyzed 59 recordings taken from two public datasets containing electrocardiographic, seismocardiographic, and gyrocardiographic signals from “Mechanocardiograms with ECG reference” and “An Open-access Database for the Evaluation of Cardio-mechanical Signals from Patients with Valvular Heart Diseases” that contain 29 and 30 recordings, respectively. HRV analysis included time and frequency domain indices and the linear models were evaluated using 5-fold stratified cross-validation. The highest sensitivity, PPV, accuracy and F1 score were observed for Logistic Regression (0.8810, 0.8819, 0.8814, 0.8812), followed by Ridge Regression (0.8805, 0.8858, 0.8814, 0.8808), and the lowest were observed for linear SVM (0.8310, 0.8318, 0.8305, 0.8305). The results showed that it is possible to distinguish healthy volunteers and patients with linear classifiers and time domain and frequency domain HRV indices obtained from ECG signals with decent performance.https://doi.org/10.1515/cdbme-2024-2144heart rate variabilityelectrocardiographyvalvular heart diseaselinear classifiers
spellingShingle Siecinski Szymon
Doniec Rafal Jan
Grzegorzek Marcin
Linear classification of healthy people and patients with valvular heart diseases based on heart rate variability indices derived from electrocardiograms
Current Directions in Biomedical Engineering
heart rate variability
electrocardiography
valvular heart disease
linear classifiers
title Linear classification of healthy people and patients with valvular heart diseases based on heart rate variability indices derived from electrocardiograms
title_full Linear classification of healthy people and patients with valvular heart diseases based on heart rate variability indices derived from electrocardiograms
title_fullStr Linear classification of healthy people and patients with valvular heart diseases based on heart rate variability indices derived from electrocardiograms
title_full_unstemmed Linear classification of healthy people and patients with valvular heart diseases based on heart rate variability indices derived from electrocardiograms
title_short Linear classification of healthy people and patients with valvular heart diseases based on heart rate variability indices derived from electrocardiograms
title_sort linear classification of healthy people and patients with valvular heart diseases based on heart rate variability indices derived from electrocardiograms
topic heart rate variability
electrocardiography
valvular heart disease
linear classifiers
url https://doi.org/10.1515/cdbme-2024-2144
work_keys_str_mv AT siecinskiszymon linearclassificationofhealthypeopleandpatientswithvalvularheartdiseasesbasedonheartratevariabilityindicesderivedfromelectrocardiograms
AT doniecrafaljan linearclassificationofhealthypeopleandpatientswithvalvularheartdiseasesbasedonheartratevariabilityindicesderivedfromelectrocardiograms
AT grzegorzekmarcin linearclassificationofhealthypeopleandpatientswithvalvularheartdiseasesbasedonheartratevariabilityindicesderivedfromelectrocardiograms