ЕFFECTIVENESS OF THE DRUG MELATONIN WOMEN OF REPRODUCTIVE AGE WITH ABNORMAL UTERINE BLEEDING AND COMBINED EXTRAGENITAL PATHOLOGY
Сurrently optimization of therapy approaches is the actual in management of women with abnormal uterine bleeding combined with extragenital pathology. Study objective: to increase the treatment effectiveness of abnormal uterine bleeding in fertile women with presence of concomitant extragenital path...
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2016-06-01
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| Series: | Акушерство, гинекология и репродукция |
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| Online Access: | https://www.gynecology.su/jour/article/view/91 |
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| author | E. N. Tananakina |
| author_facet | E. N. Tananakina |
| author_sort | E. N. Tananakina |
| collection | DOAJ |
| description | Сurrently optimization of therapy approaches is the actual in management of women with abnormal uterine bleeding combined with extragenital pathology. Study objective: to increase the treatment effectiveness of abnormal uterine bleeding in fertile women with presence of concomitant extragenital pathology by studying the hormonal levelsand to develop pathogenetically substantiated treatment regimen. Materials and Methods: a prospective trial of 96 fertile women with abnormal uterine bleeding concomitant extragenital pathology. All patients received a standard hemostatictherapy, 48 women additionally administered melatonin (Group 1), and 48 women received standard therapy without melatonin (group 2). 23 patients without any gynecologic and extragenital pathology comprised Group 3 (control group). Results: melatonin usage during treatment of uterine bleeding in fertile women with combined extragenital pathology: to increasing levels of cortisol, which indicates the possibility of a more rapid formation of the adaptation syndrome; stabilizes the endogenous melatonin; normalizes the ratio of estrogen and progesterone levels, optimizing hormonal balance, regardless of the original background and level of the breach, and thus increases the efficiency of the treatment of uterine bleeding, which is important for practical medicine. |
| format | Article |
| id | doaj-art-c9e4e76032574940a5efa9978d5b10af |
| institution | Kabale University |
| issn | 2313-7347 2500-3194 |
| language | Russian |
| publishDate | 2016-06-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Акушерство, гинекология и репродукция |
| spelling | doaj-art-c9e4e76032574940a5efa9978d5b10af2025-08-20T03:39:40ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942016-06-0183313889ЕFFECTIVENESS OF THE DRUG MELATONIN WOMEN OF REPRODUCTIVE AGE WITH ABNORMAL UTERINE BLEEDING AND COMBINED EXTRAGENITAL PATHOLOGYE. N. Tananakina0Lugansk State Medical University (Lugansk, Ukraine)Сurrently optimization of therapy approaches is the actual in management of women with abnormal uterine bleeding combined with extragenital pathology. Study objective: to increase the treatment effectiveness of abnormal uterine bleeding in fertile women with presence of concomitant extragenital pathology by studying the hormonal levelsand to develop pathogenetically substantiated treatment regimen. Materials and Methods: a prospective trial of 96 fertile women with abnormal uterine bleeding concomitant extragenital pathology. All patients received a standard hemostatictherapy, 48 women additionally administered melatonin (Group 1), and 48 women received standard therapy without melatonin (group 2). 23 patients without any gynecologic and extragenital pathology comprised Group 3 (control group). Results: melatonin usage during treatment of uterine bleeding in fertile women with combined extragenital pathology: to increasing levels of cortisol, which indicates the possibility of a more rapid formation of the adaptation syndrome; stabilizes the endogenous melatonin; normalizes the ratio of estrogen and progesterone levels, optimizing hormonal balance, regardless of the original background and level of the breach, and thus increases the efficiency of the treatment of uterine bleeding, which is important for practical medicine.https://www.gynecology.su/jour/article/view/91uterine bleedingreproductive ageextragenital pathologymelatonin |
| spellingShingle | E. N. Tananakina ЕFFECTIVENESS OF THE DRUG MELATONIN WOMEN OF REPRODUCTIVE AGE WITH ABNORMAL UTERINE BLEEDING AND COMBINED EXTRAGENITAL PATHOLOGY Акушерство, гинекология и репродукция uterine bleeding reproductive age extragenital pathology melatonin |
| title | ЕFFECTIVENESS OF THE DRUG MELATONIN WOMEN OF REPRODUCTIVE AGE WITH ABNORMAL UTERINE BLEEDING AND COMBINED EXTRAGENITAL PATHOLOGY |
| title_full | ЕFFECTIVENESS OF THE DRUG MELATONIN WOMEN OF REPRODUCTIVE AGE WITH ABNORMAL UTERINE BLEEDING AND COMBINED EXTRAGENITAL PATHOLOGY |
| title_fullStr | ЕFFECTIVENESS OF THE DRUG MELATONIN WOMEN OF REPRODUCTIVE AGE WITH ABNORMAL UTERINE BLEEDING AND COMBINED EXTRAGENITAL PATHOLOGY |
| title_full_unstemmed | ЕFFECTIVENESS OF THE DRUG MELATONIN WOMEN OF REPRODUCTIVE AGE WITH ABNORMAL UTERINE BLEEDING AND COMBINED EXTRAGENITAL PATHOLOGY |
| title_short | ЕFFECTIVENESS OF THE DRUG MELATONIN WOMEN OF REPRODUCTIVE AGE WITH ABNORMAL UTERINE BLEEDING AND COMBINED EXTRAGENITAL PATHOLOGY |
| title_sort | еffectiveness of the drug melatonin women of reproductive age with abnormal uterine bleeding and combined extragenital pathology |
| topic | uterine bleeding reproductive age extragenital pathology melatonin |
| url | https://www.gynecology.su/jour/article/view/91 |
| work_keys_str_mv | AT entananakina effectivenessofthedrugmelatoninwomenofreproductiveagewithabnormaluterinebleedingandcombinedextragenitalpathology |