Demonstration of cavitary legionnaires’ pneumonia in a renal transplant recipient
Legionella pneumophila is a potentially life-threatening infection, especially for individuals with compromised cell-mediated immunity. Typical chest CT findings include multilobed or multisegmented consolidations and ground-glass opacities, but cavitary lesions are rare. This case report details a...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-02-01
|
| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S193004332401152X |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850065752297570304 |
|---|---|
| author | Som Singh, MD Sylvestre Pineau, BS Gautam Sikka, MD |
| author_facet | Som Singh, MD Sylvestre Pineau, BS Gautam Sikka, MD |
| author_sort | Som Singh, MD |
| collection | DOAJ |
| description | Legionella pneumophila is a potentially life-threatening infection, especially for individuals with compromised cell-mediated immunity. Typical chest CT findings include multilobed or multisegmented consolidations and ground-glass opacities, but cavitary lesions are rare. This case report details a 29-year-old male renal transplant recipient who developed cavitary Legionnaires' pneumonia. His medical history includes focal segmental glomerulosclerosis and recurrent FSGS post-transplant, managed with a complex immunosuppressive regimen. Following an acute episode of allograft dysfunction treated with alemtuzumab, he developed respiratory symptoms, and initial diagnostics revealed Legionella pneumophila. Despite initial improvement, he presented with worsening symptoms and was readmitted where CT scans indicated necrotizing pneumonia with cavitary lesions. This case highlights the need for vigilant monitoring and tailored therapeutic strategies in immunocompromised patients with Legionnaires' disease. |
| format | Article |
| id | doaj-art-c9dfb4e5eadc45ee85913e2b12967c9d |
| institution | DOAJ |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-c9dfb4e5eadc45ee85913e2b12967c9d2025-08-20T02:48:55ZengElsevierRadiology Case Reports1930-04332025-02-012021090109410.1016/j.radcr.2024.10.052Demonstration of cavitary legionnaires’ pneumonia in a renal transplant recipientSom Singh, MD0Sylvestre Pineau, BS1Gautam Sikka, MD2Corresponding author.; Department of Internal Medicine, University of Texas Health Sciences Center at Houston, Houston, TX 77030 USADepartment of Internal Medicine, University of Texas Health Sciences Center at Houston, Houston, TX 77030 USADepartment of Internal Medicine, University of Texas Health Sciences Center at Houston, Houston, TX 77030 USALegionella pneumophila is a potentially life-threatening infection, especially for individuals with compromised cell-mediated immunity. Typical chest CT findings include multilobed or multisegmented consolidations and ground-glass opacities, but cavitary lesions are rare. This case report details a 29-year-old male renal transplant recipient who developed cavitary Legionnaires' pneumonia. His medical history includes focal segmental glomerulosclerosis and recurrent FSGS post-transplant, managed with a complex immunosuppressive regimen. Following an acute episode of allograft dysfunction treated with alemtuzumab, he developed respiratory symptoms, and initial diagnostics revealed Legionella pneumophila. Despite initial improvement, he presented with worsening symptoms and was readmitted where CT scans indicated necrotizing pneumonia with cavitary lesions. This case highlights the need for vigilant monitoring and tailored therapeutic strategies in immunocompromised patients with Legionnaires' disease.http://www.sciencedirect.com/science/article/pii/S193004332401152XLegionellaPneumoniaRenal transplantCavitary pneumoniaCavity |
| spellingShingle | Som Singh, MD Sylvestre Pineau, BS Gautam Sikka, MD Demonstration of cavitary legionnaires’ pneumonia in a renal transplant recipient Radiology Case Reports Legionella Pneumonia Renal transplant Cavitary pneumonia Cavity |
| title | Demonstration of cavitary legionnaires’ pneumonia in a renal transplant recipient |
| title_full | Demonstration of cavitary legionnaires’ pneumonia in a renal transplant recipient |
| title_fullStr | Demonstration of cavitary legionnaires’ pneumonia in a renal transplant recipient |
| title_full_unstemmed | Demonstration of cavitary legionnaires’ pneumonia in a renal transplant recipient |
| title_short | Demonstration of cavitary legionnaires’ pneumonia in a renal transplant recipient |
| title_sort | demonstration of cavitary legionnaires pneumonia in a renal transplant recipient |
| topic | Legionella Pneumonia Renal transplant Cavitary pneumonia Cavity |
| url | http://www.sciencedirect.com/science/article/pii/S193004332401152X |
| work_keys_str_mv | AT somsinghmd demonstrationofcavitarylegionnairespneumoniainarenaltransplantrecipient AT sylvestrepineaubs demonstrationofcavitarylegionnairespneumoniainarenaltransplantrecipient AT gautamsikkamd demonstrationofcavitarylegionnairespneumoniainarenaltransplantrecipient |