The SIX1/LDHA Axis Promotes Lactate Accumulation and Leads to NK Cell Dysfunction in Pancreatic Cancer
Background. Pancreatic cancer (PC) is a malignant cancer with poor prognosis and high mortality rate. Sine oculis homeobox homolog 1 (SIX1) participates in the development of many cancers. However, the function of SIX1 in PC is not fully understood. Methods. SIX1 expression was determined using immu...
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Main Authors: | Wanli Ge, Lingdong Meng, Shouji Cao, Chaoqun Hou, Xiaole Zhu, Dongya Huang, Qiang Li, Yunpeng Peng, Kuirong Jiang |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-01-01
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Series: | Journal of Immunology Research |
Online Access: | http://dx.doi.org/10.1155/2023/6891636 |
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